Search Results - Diagnostic+Markers+%26+Platforms

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2022-140 Label-Free Virtual HER2 Immunohistochemical Staining of Breast Tissue Using Deep Learning
SUMMARY: UCLA researchers in the Departments of Bioengineering and Electrical and Computer Engineering have developed a deep learning-based algorithm that can detect and quantify the breast cancer marker human epidermal growth factor receptor 2 (HER2) in microscopic images without the need for time-consuming immunohistochemical staining (IHC). BACKGROUND:...
Published: 8/9/2022   |   Inventor(s): Aydogan Ozcan, Yair Rivenson, Bijie Bai, Hongda Wang
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Biomarker, Bladder Cancer, Breast Cancer, Cancer, Cancer Immunotherapy, Computer Aided Learning, Diagnostic Markers & Platforms, Diagnostic Test, Fluorescence, Fluorescent Labelling, HER2/Neu, Histology, Immune System, Immunohistochemistry, Life Science Research Tools, Machine Learning, Optics, Research Methods, Unsupervised Learning
Category(s): artificial intelligence, Diagnostic Markers & Platforms, Diagnostic Markers & Platforms > immunology, Life Science Research Tools, Life Science Research Tools > research methods, Medical Imaging, Medical Imaging > fluorescence, optics/photonics
Motility-Based Label-Free Detection of Parasites in Bodily Fluids Using Holographic Speckle Analysis and Deep Learning (Case ID 2019-002)
SUMMARY: UCLA researchers in the Department of Electrical and Computer Engineering have developed deep learning-based, cost-effective, and portable optical devices that facilitate label-free, high-throughput and sensitive detection of motile parasites. BACKGROUND: Parasitic infections are a major global public health issue, but current screening...
Published: 8/5/2022   |   Inventor(s): Aydogan Ozcan, Yibo Zhang, Hatice Ceylan Koydemir
Keywords(s): Algorithm, Artificial Intelligence, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Disease, Holography, Imaging, Infection, Infectious Diseases, Infectivity, Monitoring (Medicine), Optics, Software & Algorithms
Category(s): Software & Algorithms, Software & Algorithms > image processing, Diagnostic Markers & Platforms, Diagnostic Markers & Platforms > diagnostic platform technologies (e.g. microfluidics), Therapeutics & Vaccines > infectious diseases, Medical Imaging, Medical Devices and Materials > monitoring and recording systems, Medical Devices and Materials, Life Science Research Tools
Low-Cost And Portable Uv Holographic Microscope For High-Contrast Protein Crystal Imaging
SUMMARY UCLA researchers in the Department of Electrical Engineering have developed an on-chip UV holographic imaging microscope that offers a low-cost, portable, and robust technique to image and distinguish protein crystals from salt crystals. BACKGROUND Dual-mode microscopes composed of bright-field and ultraviolet (UV) induced fluorescence modes...
Published: 7/27/2022   |   Inventor(s): Aydogan Ozcan, Aniruddha Ray, Mustafa Daloglu
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Microscopy And Imaging, Monitoring And Recording Systems, Other
Category(s): Diagnostic Markers & Platforms, Diagnostic Markers & Platforms > diagnostic platform technologies (e.g. microfluidics), Medical Devices and Materials, Medical Devices and Materials > monitoring and recording systems, Medical Imaging, other, Life Science Research Tools, Life Science Research Tools > microscopy and imaging
2020-487 Early-Detection and Classification of Live Bacteria Using Time-Lapse Coherent Imaging and Deep Learning
Summary: Researchers from UCLA’s Electrical and Computer Engineering and Bioengineering Departments have invented a novel automated system that quickly detects and classifies colonies of live bacteria in water by using deep neural networks to analyze holographic images. Background: Early identification of pathogenic bacteria in food, water,...
Published: 7/11/2022   |   Inventor(s): Aydogan Ozcan, Yair Rivenson, Hongda Wang, Hatice Ceylan Koydemir, Yunzhe Qiu
Keywords(s): Diagnostic Platform Technologies (E.G. Microfluidics), Hospital Systems And Devices, Imaging, Instrumentation & Analysis, Life Science Research Tools, Microscopy And Imaging
Category(s): artificial intelligence, Diagnostic Markers & Platforms, Electrical > Instrumentation, Electrical > Imaging, Energy & Water, Software & Algorithms
Cellphone-Based Micro-Plate Reader for Point-Of-Care ELISA Testing & High-Throughput and Automated Diagnosis of Antimicrobial Resistance
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a cost-effective cellphone-based micro-plate reader to rapidly perform antimicrobial susceptibility testing (AST) with >99% accuracy. Background: Immunoassays are biochemical tests that are conducted to measure the presence and concentration of...
Published: 7/7/2022   |   Inventor(s): Aydogan Ozcan, Dino Di Carlo, Steve Feng, Bingen Cortazar Unzaga, Brandon Berg, Haydar Ozkan, Omai Garner, Kuochao Tseng
Keywords(s): Antibacterial, Antibiotic Resistance, Antibody, Artificial Intelligence, Bacteria, Drug Resistance, ELISA, High-Throughput Screening, Immunoassay, Nanotechnology, Optics, Photonics, Point Of Care, Smartphone
Category(s): artificial intelligence, Diagnostic Markers & Platforms, Life Science Research Tools, Life Science Research Tools > antibodies, Electrical > Photonics, optics/photonics
2021-252: METHOD FOR DIAGNOSING DRY MOUTH USING BIOMARKERS
SUMMARY: UCLA researchers in the Department of Dentistry have developed a novel and simple method using saliva sampling to detect and monitor xerostomia by testing for the expression of targeted biomarkers. BACKGROUND: Xerostomia, or dry mouth, occurs when salivary glands do not produce enough saliva. Xerostomia ranges in severity from mild discomfort...
Published: 4/25/2022   |   Inventor(s): David Wong
Keywords(s):  
Category(s): Diagnostic Markers & Platforms, Diagnostic Markers & Platforms > targets and assays, Therapeutics & Vaccines > dental
2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS
Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...
Published: 3/21/2022   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo
Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays
Category(s): Diagnostic Markers & Platforms, Diagnostic Markers & Platforms > targets and assays, Diagnostic Markers & Platforms > diagnostic platform technologies (e.g. microfluidics), Life Science Research Tools, Life Science Research Tools > antibodies, Life Science Research Tools > cell lines, Life Science Research Tools > research methods, Life Science Research Tools > other reagents
2021-367 MINIATURIZED WIRELESS GASTRIC PACING WITH NON-INVASIVE ELECTROGASTROGRAPHIC MONITORING
SUMMARY: UCLA researchers in the Department of Bioengineering have developed a small wireless electrical stimulus device to treat refractory gastroparesis and monitor the stimulus delivery during treatment that is lead free and minimally invasive. BACKGROUND: Refractory gastroparesis is a medical disorder that weakens the muscular contractions of...
Published: 3/3/2022   |   Inventor(s): Parinaz Abiri, Todd Coleman, Tzung Hsiai, Andrew Perley
Keywords(s): Atrophic Gastritis, Electrical, Electrode, Gastric Acid, Gastroenterology, Gastroenterology & Digestive Disease, Human Gastrointestinal Tract, Medical Device, Neurostimulation
Category(s): Medical Devices and Materials, Medical Devices and Materials > hospital systems and devices, Electrical > Electronics, Diagnostic Markers & Platforms
2021-283 MMHEALTH: MULTIMODAL HEALTH SENSING PLATFORM
SUMMARY: UCLA researchers in the Department of Electrical and Computer Engineering have developed a system that can remotely evaluate patient symptoms and diagnose medical conditions. BACKGROUND: Ensuring that patients are accurately and efficiently diagnosed is of high clinical significance. Current methods require contact-based diagnostic tests...
Published: 2/1/2022   |   Inventor(s): Achuta Kadambi, Laleh Jalilian, Omid Abari, Maxime Cannesson, Ashley Kita, Pradyumna Chari, Adnan Armouti
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Test, Infectious Diseases, Machine Learning, Remote Sensing, Sensors
Category(s): Diagnostic Markers & Platforms, Instrumentation, Life Science Research Tools > research methods, Life Science Research Tools, Medical Devices and Materials
2021-319 GENOMIC COPY NUMBER ABERRATIONS IN ZNRF3 AS PROGNOSTIC AND PREDICTIVE BIOMARKERS FOR LOCALIZED PROSTATE CANCER
SUMMARY: Researchers from UCLA’s Departments of Human Genetics and Urology have identified a novel biomarker and actionable target for prostate cancer metastasis. BACKGROUND: Prostate cancer is one of the most commonly diagnosed cancers and the second leading cause of cancer death in men. Although most men present with localized, potentially...
Published: 1/11/2022   |   Inventor(s): Michael Fraser, Paul Boutros
Keywords(s):  
Category(s): Diagnostic Markers & Platforms, Therapeutics & Vaccines > genetic disease, Therapeutics & Vaccines > oncology
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