Search Results - alexander+spokoyny

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2020-426 PRODRUGS OF PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN

Researchers at UCLA have developed prodrugs of peripherally-acting cannabinoid (PRCBs) receptor agonists for chronic pain relief. BACKGROUND: Cannabinoids are becoming prevalent in chronic pain treatments even though current marketed cannabinoid compounds may cause psychotropic effects or central nervous system (CNS)-mediated side effects. A potential...

Published: 9/5/2023 | Inventor(s): Igor Spigelman, Alexander Spokoyny, Herbert Seltzman

Keywords(s): Cns, Drug Delivery, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics, Therapeutics > CNS and Neurology

2016-573 Photophysically Innocent Boron Cluster Ligand Scaffolds For Organic Light Emitting Diode Materials

Summary UCLA researchers have developed a novel method to using boron clusters ligands for light emitting diode materials. This is the first report of the ligand 1,1'-bis-o-carborane (bc) bound to Pt(N^N). Both C-Pt symmetrical isomers and C-Pt/B-Pt asymmetric isomers can be synthesized. Background An organic light- emitting diode (OLED) is a LED in...

Published: 7/19/2023 | Inventor(s): Alexander Spokoyny, Kent Kirlikovali, Jonathan Axtell, Alejandra Gonzalez

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Category(s): Materials > Semiconducting Materials

2018-738 ULTRASMALL BORON OXIDE NANOPARTICLES FOR BNCT

INTRO SENTENCE: UCLA researchers in the Department of Chemistry and Biochemistry have developed ultrasmall, boron oxide nanoparticles suitable for boron neutron capture therapy.TITLE: Ultrasmall boron oxide nanoparticles for boron neutron capture therapy (BNCT)BACKGROUND: Boron neutron capture therapy (BNCT) is an emerging strategy for cancer treatment....

Published: 7/19/2023 | Inventor(s): Alexander Spokoyny, Roshini Ramachandran, Jessica Logan

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Category(s): Platforms > Drug Delivery > Nanoparticles, Medical Devices > Medical Imaging > CT, Therapeutics > Vaccines

2019-336 CARBORANE-BASED HISTONE DEACETYLASE (HDAC) INHIBITORS

Carborane-Based Histone Deacetylase (HDAC) InhibitorsTech ID: 30179 / UC Case 2019-336-0SUMMARYUCLA researchers from the Department of Chemistry & Biochemistry have developed a new class of Histone Deacetylase (HDAC) inhibitors that can be tuned for isoform specificity and other properties.BACKGROUNDHistone Deacetylase (HDAC) is a ubiquitous enzyme...

Published: 7/19/2023 | Inventor(s): Alexander Spokoyny

Keywords(s): Cns, Life Science Research Tools, Other Reagents, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents, Therapeutics, Therapeutics > CNS and Neurology