Search Results - animal+imaging

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2014-9AG Wide-Field Computational Imaging of Pathology Slides Using Lensfree On-Chip Microscopy

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a wide field-of-view (FOV) computational imaging method using lens-free on-chip microscopy to efficiently and cost-effectively scan biological samples such as pathology slides. Background: Wide field-of-view (FOV) and high-resolution imaging is crucial...

Published: 7/19/2023 | Inventor(s): Aydogan Ozcan, Alon Greenbaum, Yibo Zhang, Alborz Feizi, Wei Luo

Category(s): Life Science Research Tools, Electrical, Electrical > Imaging, Life Science Research Tools > Microscopy And Imaging, Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Medical Devices > Medical Imaging

2020-158 SYSTEM AND METHOD FOR REAL-TIME MULTICOLOR SHORTWAVE INFRARED FLUORESCENCE IMAGING

UCLA researchers in the Department of Chemistry and Biochemistry have developed fluorescence imaging probes and methods to achieve multiplexed imaging in the shortwave infrared (SWIR, 1000 – 2000nm) region. The system and method developed allows high-contrast and resolution multiplexed imaging of whole animals in real-time. BACKGROUND: Real-time,...

Published: 7/19/2023 | Inventor(s): Ellen Sletten, Emily Cosco, Oliver Bruns

Keywords(s): Animal Imaging, Diagnostic Markers & Platforms, Fluorescence, Image Processing, Imaging, Instrumentation, Instrumentation & Analysis, Life Science Research Tools, Medical Imaging, Optics

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Life Science Research Tools > Lab Equipment, Diagnostic Markers, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence

2005-010 MUTATED RENILLA LUCIFERASE FOR HIGHER LIGHT OUTPUT AND ALTERED STABILITY

A Novel Renilla-Derived Luciferase with Enhanced Activity and StabilitySUMMARYUCLA researchers in the Department of Molecular and Medical Pharmacology have developed a novel luciferase variant with enhanced stability and activity.BACKGROUNDLuciferase proteins first derived from firefly are indispensable in biological research. They are used for in vivo...

Published: 7/19/2023 | Inventor(s): Anna Wu, Andreas Loening, Sanjiv Gambhir

Keywords(s): Animal Imaging, Life Science Research Tools, Medical Imaging, Microscopy And Imaging

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Animal Imaging, Medical Devices > Medical Imaging

2019-318 NONCOVALENT METHODS TO MODIFY BIOMOLECULES

INTRO SENTENCE:UCLA researchers in the Department of Chemistry and Biochemistry have designed a novel method for the sequential detection and treatment of diseases.BACKGROUND:In most clinics, the general approach to helping new patients involves two separate steps – diagnosis and treatment. The separation of treatment from diagnosis necessitates...

Published: 7/19/2023 | Inventor(s):

Keywords(s): All Types, Animal Imaging, Diagnostic Markers & Platforms, Life Science Research Tools, Medical Imaging, Oncology (Small Molecules, Peptides and Antibodies)

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Diagnostic Markers, Medical Devices > Medical Imaging, Therapeutics > Oncology > Oncology (Small Molecules)

Development and Applications of Multi-modality Engineered Antibody Fragments as New

INTRO SENTENCE:UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a method that allows the dual labeling of antibodies with an optical dye and an 18F radionuclide for multi-modality imaging.BACKGROUND:Multi-modality antibody-based imaging represents an important advance in the medical field, since it can combine...

Published: 7/19/2023 | Inventor(s):

Keywords(s): Animal Imaging, Fluorescence, Life Science Research Tools, Medical Imaging, PET

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > PET, Medical Devices > Medical Imaging > Fluorescence

2008-030 DRUG CONJUGATED MAGNETONANOPARTICLES FOR VISUALIZATION OF NEOPLASM (ONCOLOGY), CARDIAC IMAGING AND NEUROLOGICAL DISEASES AND DISORDERS...

Case No. 2008-030SUMMARYResearchers at the UCLA Semel Institute for Neuroscience and Human Behavior have developed magnetic nanoparticles (MNPs) functionalized with deoxyglucose that can be used as tissue-specific contrast agents for MRI. These novel MNPs can help physicians and researchers to differentiate neoplastic, epileptic, parkinsonian, or Alzheimer...

Published: 7/19/2023 | Inventor(s): Massoud Akhtari, Jerome Engel

Keywords(s): Animal Imaging, Cns, CT, Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Microscopy And Imaging, MRI, Oncology, PET

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > PET, Therapeutics > CNS and Neurology, Therapeutics > Oncology

2017-723 An Osteoadsorptive Fluorogenic Substrate of Cathepsin K for Imaging Osteoclast Activity and Migration

An Osteoadsorptive Fluorogenic Substrate of Cathepsin K for Imaging Osteoclast Activity and MigrationSUMMARYUCLA researchers in the Department of Dentistry have developed a novel fluorescent probe for studying the role of osteoclasts in bone diseases and for detecting the early onset of bone resorption by targeting an important protein Cathepsin K....

Published: 7/19/2023 | Inventor(s): Ichiro Nishimura, Akishige Hokugo, Charles Mckenna, Eric Richard, Boris Kashemirov, Kenzo Morinaga

Keywords(s): Animal Imaging, Autoimmune, Diagnostic Markers & Platforms, Drug Delivery, Fluorescence, Life Science Research Tools, Medical Imaging, Orthopaedics

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Drug Delivery, Therapeutics > Autoimmune, Medical Devices > Medical Imaging > Fluorescence, Therapeutics > Orthopaedics

2017-708 Modular Miniature Microscopy System

Modular Miniature Microscopy SystemSUMMARYUCLA researchers have developed a modular miniature microscopy system for brain imaging in behaving animals.BACKGROUNDThe light microscope is traditionally an instrument of substantial size and expense. Its miniaturized integration would enable many new applications based on mass-producible, tiny microscopes....

Published: 7/19/2023 | Inventor(s): Peyman Golshani, Alcino Silva, Baljit Khakh, Tristan Shuman, Daniel Aharoni, Denise Cai

Keywords(s): Animal Imaging, Life Science Research Tools, Medical Devices and Materials, Microscopy And Imaging, Monitoring And Recording Systems

Category(s): Life Science Research Tools > Animal Imaging, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Monitoring And Recording Systems

2016-151 Ultra-Dense Electrode-Based Brain Imaging System with High Spatial and Temporal Resolution

SUMMARYUCLA researchers in the Department of Bioengineering have developed a novel integrated brain imaging system that utilizes an ultra-dense electrode-based device. This system provides high resolution of functional brain images spatially and temporally.BACKGROUNDBrain imaging using regular MRI and fMRI is part of the $6 billion medical magnetic...

Published: 7/19/2023 | Inventor(s): Ying Li, Wentai Liu, Jing Qin, Chih Wei Chang, Yi-Kai Lo

Keywords(s): All Types, Animal Imaging, Cns, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Monitoring And Recording Systems

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Diagnostic Markers, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > CNS and Neurology

Preparation Of Functionalized Polypeptides, Peptides, And Proteins By Alkylation Of Thioether Groups

SummaryUCLA researchers in the Departments of Chemistry, Physics, and Bioengineering, led by Dr. Tim Deming of the Bioengineering Department, have developed new methods for adding different functional groups on polypeptides. The UCLA researchers have used this method to create a platform to create and modify nanoscale vesicles and hydrogels for use...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Jessica Kramer

Keywords(s): Animal Imaging, Drug Delivery, Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Nanoparticles, Other, Surgical Tools

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Surgical Tools, Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles

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