Search Results - antibody

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Antibody-Drug Conjugates Targeting Stem Cell-Derived Cancer Cells and Tumor Stroma (UCLA Case No. 2020-790)
UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a versatile antibody-drug conjugate platform utilizing a novel monoclonal antibody that is highly specific at targeting cancer cells and rapidly internalized by those cells for an effective anti-tumor response. BACKGROUND: For decades, an absolute majority of...
Published: 2/13/2024   |   Inventor(s): Robert Damoiseaux, Hans Ulmert, Hans David Ulmert, Norbert Peekhaus, Liqun Mao, Claire Storey
Keywords(s): Antibody, diagnostic radionuclides, Imaging, Life Science Research Tools, Medical Imaging, Mesenchymal Stem Cell Derived Cancer Cells, Oncology, PET, therapeutic radionuclides, Tumor microenvironment, Tumor Stroma
Category(s): Medical Devices > Medical Imaging > PET
Cellphone-Based Micro-Plate Reader for Point-Of-Care ELISA Testing & High-Throughput and Automated Diagnosis of Antimicrobial Resistance
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a cost-effective cellphone-based micro-plate reader to rapidly perform antimicrobial susceptibility testing (AST) with >99% accuracy. Background: Immunoassays are biochemical tests that are conducted to measure the presence and concentration of...
Published: 7/19/2023   |   Inventor(s): Aydogan Ozcan, Dino Di Carlo, Steve Feng, Bingen Cortazar Unzaga, Brandon Berg, Haydar Ozkan, Omai Garner, Kuochao Tseng
Keywords(s): Antibacterial, Antibiotic Resistance, Antibody, Artificial Intelligence, Bacteria, Drug Resistance, ELISA, High-Throughput Screening, Immunoassay, Nanotechnology, Optics, Photonics, Point Of Care, Smartphone
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Diagnostic Markers, Optics & Photonics, Software & Algorithms > Artificial Intelligence & Machine Learning
2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS
Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...
Published: 7/19/2023   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo
Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies