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PAK4 in Cancer Immune Exclusion
Case 2018-209Researchers at the UCLA David Geffen School of Medicine have proposed that T cell tumor infiltration and the anti-tumor activity of anti-PD-1/PD-L1-based immunotherapy to be modulated through kinase PAK4 activity. BACKGROUNDThe p21-activated kinase 4 (PAK4) is a member of the PAK family of serine/threonine kinases, which are important...
Published: 7/19/2023   |   Inventor(s): Antoni Ribas, Catherine Grasso
Keywords(s): Immunotherapy, Life Science Research Tools, Medical Devices and Materials, Oncology, Therapeutics & Vaccines
Category(s): Life Science Research Tools, Medical Devices, Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology