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2021-355 Magnetically Activated Individual Cell Sorting Using Spin Orbit Torque

SUMMARY: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a magnetically activated cell sorting method with high throughput and low-cost operation. BACKGROUND: The use of cell sorting techniques has become indispensable for many applications in biology and biomedicine. Cell sorting is particularly important...

Published: 7/19/2023 | Inventor(s): Abdon Sepulveda, Victor Estrada, Ruoda Zheng, Yilian Wang

Keywords(s): Cancer Immunotherapy, Chemical, Diagnostic Markers & Platforms, High-Throughput Screening, Imaging, Magnetic Field, Materials, Nanomaterials, Nanotechnology, T Cell

Category(s): Life Science Research Tools > Microscopy And Imaging, Materials > Nanotechnology, Life Science Research Tools, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging, Medical Devices > Medical Imaging

2020-408: sAPPalpha Targeted Therapeutics for Alzheimer’s Disease

UCLA researchers from the Department of Neurology have developed a novel application of two compounds that target the upstream formation of toxic amyloid-beta oligomers for the effective treatment of Alzheimer’s disease. BACKGROUND: Alzheimer’s Disease (AD) is the most common age-related neurodegenerative disorder currently affecting ~6...

Published: 7/19/2023 | Inventor(s): Varghese John, Sujyoti Chandra

Keywords(s): Chemical, Cns, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > CNS and Neurology

2020-478 CONVERSION OF HETEROCYCLES TO NOVEL POLYMERS CONTAINING STRAINED FUNCTIONALITY AND CAPACITY FOR POST-POLYMERIZATION MODIFICATION

UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel method for the conversion of Dewar heterocycles to versatile monomers with capacity for post-polymerization chemistry. BACKGROUND: Post-polymerization modifications are crucial in the development of synthetic materials for electronic, biomedical, and feedstock...

Published: 7/19/2023 | Inventor(s): Hosea Nelson

Keywords(s): Catalysts, Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Functional Materials

Category(s): Chemical > Catalysts, Chemical > Polymers, Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals

2020-172 MICROBIAL PRODUCTION OF CANNABINOID PRECURSOR OLIVETOLIC ACID AND ITS ANALOGUES

UCLA researchers in the Department of Chemical & Biomolecular Engineering have developed a novel method for the production of cannabinoid precursor olivetolic acid for the scalable synthesis of cannabinoids. BACKGROUND: Cannabinoids, the chemicals found in the cannabis plant, are widely recognized for their medical applications to alleviate pain....

Published: 7/19/2023 | Inventor(s): Yi Tang

Keywords(s): Chemical, Hydrocarbons, Pain Treatment, Personal Care / Home Care , Therapeutics & Vaccines

Category(s): Chemical, Therapeutics > CNS and Neurology

2009-554 COMPLEX MIXED LIGAND OPEN FRAMEWORK MATERIALS

Case 2009-554UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel multifarious mixed functionalized metal-organic framework (MOF), which has been demonstrated to be successful in gas storage and separation.BACKGROUNDAdding complexity and increasing the number of building units to crystalline structures usually leads...

Published: 7/19/2023 | Inventor(s): Omar Yaghi, Christian Doonan, Hexiang Deng

Keywords(s): Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Materials

Category(s): Chemical > Industrial & Bulk Chemicals

2011-250 METAL TRIAZOLITES

Case No. 2011-250SUMMARYUCLA researchers in the Department of Chemistry and Biochemistry have developed a novel metal-organic framework (MOF) using triazole ligands that allows for facile modification with a variety of metals, which has unique gas separation and adsorption properties.BACKGROUNDPrevious MOFs with advantageous porosity and stability have...

Published: 7/19/2023 | Inventor(s): Omar Yaghi, Fernando Uribe Romo, David Britt, Felipe Gandara Barragan

Keywords(s): Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Metals

Category(s): Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals, Chemical > Chemical Sensors, Energy & Environment > Energy Storage > Gas Storage

Enantioseparation of Amino Acids Using a Chiral Recognition Polymer

Case 1998-601BACKGROUNDEnantioseparations are becoming increasingly important because the U.S. Food and Drug Administration has declared if a drug is chiral, the biological effects of both enantiomers must be determined. Many procedures for resolutions of D, L-amino acids have been documented on an analytical scale. The limitations of these methods...

Published: 7/19/2023 | Inventor(s): Richard Kaner, Hailan Guo, Charles Knobler

Keywords(s): Chemical, Reaction Technologies

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