Search Results - gastroenterology+%26+digestive+disease

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2021-367 MINIATURIZED WIRELESS GASTRIC PACING WITH NON-INVASIVE ELECTROGASTROGRAPHIC MONITORING
SUMMARY: UCLA researchers in the Department of Bioengineering have developed a small wireless electrical stimulus device to treat refractory gastroparesis and monitor the stimulus delivery during treatment that is lead free and minimally invasive. BACKGROUND: Refractory gastroparesis is a medical disorder that weakens the muscular contractions of...
Published: 7/19/2023   |   Inventor(s): Parinaz Abiri, Todd Coleman, Tzung Hsiai, Andrew Perley
Keywords(s): Atrophic Gastritis, Electrical, Electrode, Gastric Acid, Gastroenterology, Gastroenterology & Digestive Disease, Human Gastrointestinal Tract, Medical Device, Neurostimulation
Category(s): Diagnostic Markers, Medical Devices, Electrical > Wireless
SYNERGISM BETWEEN PROTON PUMP INHIBITORS AND A GI PEPTIDE IN REDUCING ACID SECRETION
Case 2000-093UCLA researchers in the Department of Medicine have discovered a novel method to improve the efficacy of proton pump inhibition. BACKGROUND:A vast number of pathological conditions are characterized by over-secretion of gastric acid, such as Zollinger/Ellison syndrome (ZES), gastroesophageal reflux disease (GERD), peptic ulcer disease,...
Published: 7/19/2023   |   Inventor(s): Joseph Pisegna
Keywords(s): Gastroenterology & Digestive Disease, Renal, Therapeutics & Vaccines
Category(s): Therapeutics > Gastroenterology, Therapeutics > Renal
2019-519 MICROBIOME-BASED MODULATION OF SENSORY NEURONAL ACTIVITY
UCLA researchers in the Department of Integrative Biology and Physiology have begun to elucidate the molecular pathways for communication between the gut microbiota and the brain, serving as potential therapeutic targets for the treatment of various neurological diseases.BACKGROUND: The gut microbiota is recognized as an important regulator of brain...
Published: 2/16/2024   |   Inventor(s): Elaine Hsiao
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease
Category(s): Therapeutics > Gastroenterology
2019-520 MATERNAL GUT MICROBIOTA REGULATION OF NEURODEVELOPMENT AND ADULT SENSORY BEHAVIOR
UCLA Researchers in the Department of Integrative Biology and Physiology have determined the necessary role for maternal gut microbes in neurodevelopment and that select microbes may prevent abnormal neurodevelopmental phenotypes.BACKGROUND: The gastrointestinal tract and brain are intimately linked, and in the past decade there have been increasing...
Published: 2/16/2024   |   Inventor(s): Elaine Hsiao, Helen Vuong
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease
Category(s): Therapeutics > Gastroenterology
2018-920 INTRA-PROCEDURE IMAGE-BASED FLOW QUANTIFICATION (FOR TREATMENT EVALUATION)
INTRODUCTION:UCLA researchers in the Department of Radiology have developed a new method for analyzing portal vein blood blow at transjugular intrahepatic portosystemic shunt (TIPS) creation.BACKGROUND:TIPS creation is a common interventional method for the treatment of portal hypertension. However, post-procedure complications can arise, which often...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s): Diagnostic Markers & Platforms, Gastroenterology & Digestive Disease, Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools > Research Methods, Therapeutics > Gastroenterology
A Wearable Platform for In-Situ Analysis of Hormones
UC Case No. 2018-657SUMMARY:UCLA researchers in the Department of Electrical and Computer Engineering have developed a highly sensitive, wearable hormone monitoring platform.BACKGROUND:Biofluid levels provide insight for monitoring depression, reproduction, and stress. Invasive methods are used to detect low-concentration biofluids. However, realizing...
Published: 7/19/2023   |   Inventor(s): Sam Emaminejad, Sanaz Pilehvar
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Endocrinology, Gastroenterology & Digestive Disease, Life Science Research Tools, Medical Devices and Materials, Psychiatry / Mental Health
Category(s): Medical Devices > Monitoring And Recording Systems, Platforms > Diagnostic Platform Technologies, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology, Therapeutics > Psychiatry And Mental Health
2019-463 PREVENTION OF THE LATE COMPLICATIONS OF ACUTE PANCREATITIS
SummaryUCLA researchers in the Department of Medicine and Surgery have developed a novel therapeutic for the prevention of late inflammatory complications in severe acute pancreatitis patients.BackgroundAcute pancreatitis, or sudden inflammation of the pancreas, a disease generally caused by gallstones or alcohol abuse, is a common reason for hospitalization...
Published: 7/19/2023   |   Inventor(s): Jonathan Kaunitz, Yasutada Akiba
Keywords(s): Endocrinology, Gastroenterology & Digestive Disease, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
2018-578 Epigenetic Profile-Based Biomarkers for Irritable Bowel Syndrome
SummaryUCLA researchers from the Vatche and Tamar Manoukian Division of Digestive Diseases have discovered an innovative approach to diagnose irritable bowel syndrome. This method uses a set of epigenetic profiles as biomarkers and is highly sensitive compared to conventional diagnostic methodologies. BackgroundIrritable bowel syndrome (IBS) affects...
Published: 7/19/2023   |   Inventor(s): Lin Chang, Swapnali Joshi
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Gastroenterology & Digestive Disease
Category(s): Diagnostic Markers, Platforms > Diagnostic Platform Technologies, Therapeutics > Gastroenterology
Flexible Stretchable Electrode And Recording Method For Gastrointestinal Prostheses
SummaryUCLA researchers in the Department of Bioengineering and Surgery have developed an electrode for stimulation and recording of intestinal peristalsis that uses a novel impedance-based sensing method.BackgroundThe gastrointestinal (GI) system is crucial for the digestion and processing of food and nutrients that enter the body. Food is moved along...
Published: 7/19/2023   |   Inventor(s): Benjamin Wu, Chih Wei Chang, James Dunn, Justin Wagner, Wentai Liu, Yi Kai Lo
Keywords(s): Gastroenterology & Digestive Disease, Medical Devices and Materials, Monitoring And Recording Systems
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > Gastroenterology
2019-004 METHODS TO REGULATE COLONIZATION OF SELECT BACTERIA OF THE MICROBIOME / MICROBE-BASED MODULATION OF LIPID AND STEROID METABOLISM
SummaryUCLA researchers in the Department of Integrative Biology and Physiology have identified a novel function of serotonin in regulating colonization of select bacterial species in the gut microbiome, and have identified specific bacteria that may modulate host intestinal lipid and steroid metabolism.BackgroundSerotonin, or 5-hydroxytryptamine (5-HT)...
Published: 7/19/2023   |   Inventor(s): Elaine Hsiao
Keywords(s): Gastroenterology & Digestive Disease, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Gastroenterology
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