Search Results - john+lee

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Targeting Prostate Cancer with a Novel T-Cell Receptor and Tissue-Specific Cancer Antigens for Improved Immune Response (UCLA Case No. 2022-070)
Researchers from UCLA’s Department of Microbiology, Immunology, & Molecular Genetics (MIMG), and the department of Molecular and Medical Pharmacology have identified a set of tissue-specific antigens which have been used to isolate and characterize a group of novel T-cell receptors (TCRs) which target prostate cancer specifically. Furthermore,...
Published: 2/26/2024   |   Inventor(s): Owen Witte, Zhiyuan Mao, Jami Witte, Pavlo Nesterenko, John Lee
Keywords(s): Cancer, cancer antigen, Peptide, peptides, prostate cancer, protein, t-cells
Category(s): Therapeutics, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
2015-288 TRP: Derivation of a Human Neuroendocrine Prostate Cancer Cell Line with Defined Oncogenic Drivers
Derivation Of A Human Neuroendocrine Prostate Cancer Cell Line With Defined Oncogenic DriversSUMMARYResearchers at UCLA have developed a malignant neuroendocrine prostate cancer cell line that was derived from benign human prostate tissue and transformed with the oncogenes MYCN and myristoylated AKT1.BACKGROUNDHuman cell lines are an important component...
Published: 7/19/2023   |   Inventor(s): Owen Witte, John Lee
Keywords(s):  
Category(s): Life Science Research Tools, Life Science Research Tools > Cell Lines
2018-571 SURFACEOME PROFILING OF ADVANCED PROSTATE CANCER TO IDENTIFY TARGET ANTIGENS FOR IMMUNE-BASED THERAPY
Surfaceome Profiling Of Advanced Prostate Cancer To Identify Target Antigens For Immune-Based TherapySUMMARYDr. Witte and colleagues at UCLA have developed a novel approach to identify surface biomarkers and targetable antigens in prostate cancer by combining multiple omics analyses across different cell lines.BACKGROUNDProstate cancer is the most common...
Published: 3/19/2024   |   Inventor(s): Owen Witte, John Lee, Nathanael Bangayan
Keywords(s): Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods