Search Results - matteo+pellegrini

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2019-863 METHODS CONCERNING ONGOING TREATMENT FOR CANCER

UCLA researchers in the Department of Molecular, Cell, and Developmental Biology have developed a novel biomarker detection method for circulating blood cell-free RNA. BACKGROUND: Approximately 39% of men and women will be diagnosed with cancer at some point during their lifetimes. Circulating tumor cell-free DNA (cfDNA) is being increasingly used...

Published: 7/19/2023 | Inventor(s): Matteo Pellegrini, Eri Srivatsan

Keywords(s): Diagnostic Markers & Platforms, Life Science Research Tools, Nucleic Acid Platform Systems, Nucleic Acids, Oncology

Category(s): Life Science Research Tools > Plasmids/Vectors, Life Science Research Tools, Diagnostic Markers, Platforms > Drug Delivery > Nucleic Acids

2017-503 USING DNA METHYLATION MARKERS TO PREDICT CLINICALLY IMPORTANT TRAITS IN MAMMALS

Using DNA Methylation Markers To Predict Clinically Important Traits In MammalsSUMMARYUCLA researchers in the Department of Molecular, Cell, and Developmental Biology have found association of DNA methylation with metabolic syndrome traits in human adipose tissue samples using epigenome-wide association studies (EWAS).BACKGROUNDThe genome-wide association...

Published: 7/19/2023 | Inventor(s): Steve Jacobsen, Matteo Pellegrini, Aldons Lusis

Keywords(s): Life Science Research Tools, Research Methods

Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods

2016-882 HIGH THROUGHPUT DIGITAL CELL QUANTIFICATION OF IMMUNE CELL SUBSETS VIA EPIGENETIC MARKERS

High Throughput Digital Cell Quantification Of Immune Cell Subsets Via Epigenetic MarkersSUMMARYUCLA researchers in the Department of Molecular, Cell, and Developmental Biology have developed a novel high-throughput method for the quantification of immune cell subtype.BACKGROUNDQuantification of leukocytes (white blood cells) among peripheral blood...

Published: 7/19/2023 | Inventor(s): Dennis Montoya, Matteo Pellegrini

Keywords(s): Autoimmune, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Immunology

Category(s): Diagnostic Markers, Diagnostic Markers > Immunology, Platforms > Diagnostic Platform Technologies, Therapeutics > Autoimmune

Polycytotoxic T Cells

Case 2016-676UCLA researchers in the Department of Dermatology have characterized a novel subset of CD8+ T cells, termed polycytotoxic, that mediate killing of intracellular pathogens.BACKGROUNDCD8+ T cells are known to engage in cytotoxic activity, where they use pore-forming proteins and proteases (granzyme B, granulysin, and perforin) to induce apoptosis...

Published: 7/19/2023 | Inventor(s): Robert Modlin, Matteo Pellegrini, Samuel Balin, Steffen Stenger

Keywords(s): Autoimmune, Immunology, Infectious Diseases, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Therapeutics, Diagnostic Markers > Immunology, Therapeutics > Autoimmune, Therapeutics > Infectious Diseases