Search Results - musculoskeletal+disease

17 Results Sort By:
2022-298 Implanted Digital Prosthesis
Summary: UCLA Researchers in the Department of Mechanical and Aerospace Engineering have developed a novel finger prosthetic attachment mechanism and skin-transfer procedure that allows for better prosthetic motion and functionality while allowing the user to feel “natural” sensations. Background: Limb amputations typically cause a loss...
Published: 12/8/2023   |   Inventor(s): Tyler Clites, Gracia Lai, Kodi Azari, Lauren Wessel
Keywords(s): Biosensor, Medical Device, Medical Devices and Materials, Musculoskeletal Disease, Orthopedics and Prosthetics (O & P), Prosthesis, Prosthetics, Sensors, Sensory System, Smart medical device, wearable medical device
Category(s): Materials, Materials > Functional Materials, Materials > Nanotechnology, Mechanical, Mechanical > Robotics, Medical Devices, Medical Devices > Neural Stimulation, Medical Devices > Surgical Tools, Therapeutics, Therapeutics > Musculoskeletal Disease, Medical Devices > Prosthetics
2017-798 Virtual Reality Training Tasks Used For Stroke Rehabilitation
SUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a set of virtual reality training tasks that can be used for rehabilitation for post-stroke patients.BACKGROUNDStroke is a leading cause of death and disability around the world, and the majority of survivors experience chronic motor deficits. Considerable...
Published: 7/19/2023   |   Inventor(s): Yang Shen, Jacob Rosen
Keywords(s): Mechanical Systems, Musculoskeletal Disease, Robotics, Software & Algorithms, Therapeutics & Vaccines
Category(s): Mechanical > Mechanical Systems, Software & Algorithms, Therapeutics, Therapeutics > Musculoskeletal Disease
2019-898 NEURAL CREST STEM CELL THERAPIES FOR DENERVATION ATROPHY
UCLA researchers in the Department of Bioengineering have developed an innovative cell-based therapy addressing the recovery from denervation atrophy by intramuscularly delivering neural crest stem cells in various constructs.BACKGROUND:Muscular denervation atrophy of various etiologies can result in weakness or loss of functional independence, as well...
Published: 7/19/2023   |   Inventor(s): Song Li, Yuan-Yu Hsueh
Keywords(s): Musculoskeletal Disease, Therapeutics & Vaccines
Category(s): Therapeutics > Musculoskeletal Disease
2019-540 ANTI CELLULAR STRESS TREATMENT TO IMPROVE PULMONARY FUNCTION IN DISORDERS WITH ER STRESS
INTRODUCTION: UCLA researchers in the Department of Orthopedic Surgery have studied a series of anti-stress compounds that ameliorate the genetic defects of patients with Osteogenesis Imperfecta. BACKGROUND: Over the past decade researchers have begun to discover a common underlying pathway for several diseases, Endoplasmic Reticulum (ER) stress. The...
Published: 9/14/2023   |   Inventor(s): Ivan Duran Jimenez
Keywords(s): Musculoskeletal Disease, Therapeutics & Vaccines
Category(s): Therapeutics > Musculoskeletal Disease
2006-585 DETOXIFIED AND OSTEOCONDUCTIVE BONE CEMENT
INTRO SENTENCE: UCLA researchers have developed a novel bone cement material for the treatment of osteoporotic fractures and degenerative joint disorders.BACKGROUND:Bone cement is a critical component of various types of orthopedic surgery that is used as spacers and for fixation of implants. Bone cement can be loaded with antibiotics to help with the...
Published: 9/20/2023   |   Inventor(s): Takahiro Ogawa, Anahid Jewett
Keywords(s): Medical Devices and Materials, Musculoskeletal Disease
Category(s): Therapeutics > Musculoskeletal Disease
Methods for Fabricating Modular Hydrogels from Macromolecules with Orthogonal Physico-chemical Responsivity
INTRO SENTENCE:UCLA researchers in the Department of Bioengineering have developed novel methods to construct modular hydrogels with orthogonal porosity and stiffness.BACKGROUND:Hydrogels are an important platform for mimicking extracellular matrix environments in many tissue engineering applications. However, the existing bulk hydrogels typically feature...
Published: 7/19/2023   |   Inventor(s):  
Keywords(s): Life Science Research Tools, Medical Devices and Materials, Microfluidics And Mem's, Musculoskeletal Disease
Category(s): Life Science Research Tools, Life Science Research Tools > Microfluidics And Mems, Medical Devices, Therapeutics > Musculoskeletal Disease
2018-465 ANTIBODY-FREE PROTOCOL FOR GENERATION OF HIGHLY EXPANDABLE, NON-FIBROADIPOGENIC MESODERMAL PRECURSORS FROMHUMAN PLURIPOTENT STEM CELLS FOR TREATMENT
Antibody-Free Protocol For Generation Of Highly Expandable, Non-Fibroadipogenic Mesodermal Precursors from Human Pluripotent Stem Cells For TreatmentTech ID: 30170 / UC Case 2018-465-0SUMMARYUCLA researchers in the Department of Orthopaedic Surgery have developed a novel method to generate mesodermal precursors from human pluripotent stem cells to treat...
Published: 7/19/2023   |   Inventor(s): Ayelet Dar, Bruno Peault, Frank Petrigliano
Keywords(s): Musculoskeletal Disease, Stem Cells / Regenerative Medicine, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Musculoskeletal Disease
Small Molecules That Facilitate Exon Skipping (UCLA Case No. 2014-258)
SUMMARYUCLA researchers in the Departments of Microbiology, Immunology, and Molecular Genetics, and Human Genetics have discovered a novel small molecule therapy that facilitates treatment of Duchene Muscular Dystrophy.BACKGROUNDDuchenne Muscular Dystrophy (DMD) is a genetic disorder caused by a mutation in the dystrophin gene. In DMD patients, muscles...
Published: 2/10/2024   |   Inventor(s): Stanley Nelson, M. Carrie Miceli, Genevieve Kendall
Keywords(s): Musculoskeletal Disease, Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Musculoskeletal Disease
2013-304 ELECTRICAL CHARGE BALANCING SCHEME FOR FUNCTIONAL STIMULATION USING PULSE WIDTH COMPENSATION
Electrical Charge Balancing Scheme For Functional Stimulation Using Pulse Width CompensationTech ID: 30167 / UC Case 2013-304-0SUMMARYUCLA researchers in the Department of Bioengineering have developed a novel electrical charge cancellation scheme to effectively remove residual charge on an electrode, achieving greater precision for lesser hardware...
Published: 7/19/2023   |   Inventor(s): Wentai Liu, Kuanfu Chen, Richard Hill, Yi Kai Lo
Keywords(s): Cns, Electronics & Semiconductors, Medical Devices and Materials, Musculoskeletal Disease
Category(s): Electrical > Electronics & Semiconductors, Electrical > Electronics & Semiconductors > Circuits, Medical Devices, Therapeutics > CNS and Neurology, Therapeutics > Musculoskeletal Disease
2010-725 MURINE FEMORAL CRITICAL DEFECT MODEL
Case No. 2010-725SUMMARYUCLA researchers in the Department of Orthopaedic Surgery have developed an implant system for bone fracture in the mouse femur as a model of intramembranous bone healing.BACKGROUNDInternal fixation systems (usually plates and screws) are surgically implanted for the purpose of repairing bone following a fracture. Open reduction...
Published: 7/19/2023   |   Inventor(s): Thomas Kremen
Keywords(s): Animal Models, Life Science Research Tools, Musculoskeletal Disease
Category(s): Life Science Research Tools > Animal Models, Life Science Research Tools, Therapeutics > Musculoskeletal Disease
1 2