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A Wearable On-Eyelid Sensor Network for Vestibular-Ocular Reflex Assessment (Case No. 2023-166)

Summary: UCLA researchers in the Department of Bioengineering have developed an ultra-thin, self-powered, waterproof, biocompatible, and sensitive on-eyelid sensor network for wireless eye movement detection, enhancing vestibular diagnostics. Background: The human balance system relies on the interaction of the vestibular system with the visual and...

Published: 4/19/2024 | Inventor(s): Jun Chen, Jing Xu

Keywords(s): diseases of the eye, eye motion, eye movement disorders, eye tracking, gaze fixation, magnetoelastic effect, magnetoelastic sensor, on-eyelid sensor, peripheral vestibular disorders, vestibular pathology assessment, Vestibular-Ocular Reflex (VOR)

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics, Electrical, Electrical > Signal Processing, Electrical > Sensors

Kaposi Sarcoma Associated Herpesvirus Vaccine Development (UCLA Case No. 2023-038)

UCLA researchers in the Department of Molecular and Medical Pharmacology have a novel discovery showing the potential benefit of engaging complement-mediated antibody functions in future KSHV vaccine development. BACKGROUND: Kaposi Sarcoma Associated Herpesvirus (KHSV) is the etiological agent for cancers such as Kaposi Sarcoma (KS) and primary...

Published: 4/16/2024 | Inventor(s): Ting-Ting Wu

Keywords(s): herpes, herpesvirus, kaposi sarcoma, Vaccines

Category(s): Therapeutics > Vaccines

High Performance Composite Membranes (Case No. 2023-303)

Summary: UCLA researchers in the Department of Civil and Environmental Engineering have developed a novel, compaction-resistant reverse osmosis membrane for desalination under high pressures. Background: Access to safe drinking water is of utmost importance for everyone, and by 2025 half of the world’s population will live in areas where demand...

Published: 4/16/2024 | Inventor(s): Eric Hoek, Jishan Wu

Keywords(s):

Category(s): Energy & Environment, Energy & Environment > Water Monitoring & Treatment

Methods and Compositions for Modification of the HPRT Locus (UCLA Case No. 2013-570)

UCLA researchers have developed a gene editing strategy and methodology based on nuclease-based insertion. BACKGROUND: Gene therapies are the forefront of therapeutic advancements for debilitating diseases. However, delivery and insertion of the therapeutic transgene are major hurdles that must be solved to effectively implement this technology....

Published: 4/12/2024 | Inventor(s): Noriyuki Kasahara

Keywords(s): Gene delivery, Gene Editing Systems, Gene Therapy

Category(s): Therapeutics > Gene Therapy And Editing

A New ADC Architecture (Case No. 2023-276)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel analog-digital conversion (ADC) Architecture that achieves high-speed, high-resolution signal conversion with reduced power consumption and increased linearity. Background: High-speed, high-resolution analog-digital converters (ADCs) are what...

Published: 4/11/2024 | Inventor(s): Utkarsh Sharma, Behzad Razavi

Keywords(s): Computer Architecture, Consumer Electronics, Digital Electronics, Digital Signal Processing, Integrated Circuit, processor design, quantum communication, Quantum Computer, Quantum Dot, quantum error correction (QEC), quantum incompressible fluid, quantum key, quantum network, quantum processing, quantum processor, Signal Processing, trapped ion quantum processor

Category(s): Electrical > Signal Processing, Electrical > Computing Hardware

Summary: UCLA researchers have developed a software to accelerate vaccine clinical trial processes by modeling disease behavior and targeting future trial participants. Background: Vaccine clinical trials are time-intensive processes; ones that may be necessary during active pandemics in which time is of short supply. One of the primary factors contributing...

Published: 4/9/2024 | Inventor(s): Akihiro Nishi

Keywords(s): Bioinformatics, Clinical Trial, Live attenuated vaccine, Public Health, Simulation & Modeling, Software & Algorithms, Therapeutics & Vaccines, Vaccines

Category(s): Software & Algorithms > Statistical Models, Software & Algorithms > Bioinformatics

Cell Type Scanner (UCLA Case No. 2021-115)

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel technology for spatial cell-type mapping in 2D and 3D tissue samples. BACKGROUND: Cell type mapping has become an integral component for many biomedical research studies and diagnostic technologies. However, a major challenge in single cell data is accurately...

Published: 4/8/2024 | Inventor(s): Roy Wollman

Keywords(s): 3D tissue imaging, cell mapping, Principal component analysis, RNA imaging, single cell analysis, Single cell data

Category(s): Life Science Research Tools > Research Methods, Software & Algorithms > Data Analytics

DNA Oligo Implementation of Multi-Layer Perception (UCLA Case No. 2021-175)

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method for an artificial neural network to solve DNA problems of regression and classification. BACKGROUND: Organisms have diverse cell types that need to be distinguished in a clinical setting. Different cell types are known to express different molecular markers...

Published: 4/8/2024 | Inventor(s): Roy Wollman

Keywords(s): cell type identification, DNA oligomer, FISH, neural network

Category(s): Life Science Research Tools > Microscopy And Imaging

Detection of Dicrotic Notch in Arterial Pressure and Photoplethysmography Signals Using Iterative Envelope Mean Filter (Case No. 2024-034)

Summary: UCLA Researchers in the Department of Anesthesiology have developed an iterative envelope mean (IEM) method for the detection of specific features in arterial pressure monitoring applications. Background: The cardiac cycle consists of the distinct systolic and diastolic phases. The transition from the contracted, systolic phase to the...

Published: 4/8/2024 | Inventor(s): Maxime Cannesson, Ravi Pal, Akos Rudas, Jeffrey Chiang, Sungsoo Kim

Keywords(s): arrhythmia, arterial blood pressure (ABP), cardiac cycle, Cardiac Electrophysiology, Cardiac failure, Cardiac Magnetic Resonance Imaging, cardiometabolic disease, cardiopulmonary illness, Cardiovascular, Cardiovascular Disease, Cardiovascular Disease Nephropathy, cardiovascular modeling, cardiovascular prediction, cardiovascular therapeutic solution, diastolic, diastolic phase peak, dicrotic notch, feature extraction tool, iterative envelope method (IEM), Medical Device, medical device cardiac monitoring, Medical Device Poly(Methyl Methacrylate), Medical Devices and Materials, non-invasive cardiac monitoring, photoplethysmography (PPG), Smart medical device, systolic, tachycardia, wearable medical device, wearable medical devices

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms, Platforms > Diagnostic Platform Technologies, Software & Algorithms, Diagnostic Markers > Targets And Assays, Diagnostic Markers

Multimodal Sensory System for Intraocular Surgery (Case No. 2024-014)

Summary: UCLA researchers in the Department of Mechanical Engineering have developed an intraocular device for accurate and precise sensing during intraocular surgical procedures. Background: Intraocular surgical procedures rely on accurate imaging of the surgical environment for improved patient outcome. Traditional imaging modalities include mounting...

Published: 4/11/2024 | Inventor(s): Tsu-Chin Tsao, Yuting Lai, Aya Barzelay, Steven Schwartz, Mia Sara-Shannon Reyes, Yasamin Foroutani

Keywords(s):

Category(s): Electrical, Electrical > Sensors, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Monitoring And Recording Systems

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