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Silicon Nanovolcanos for Gene Delivery with High Efficiency and Cell Viability

INTRO SENTENCE: UCLA researchers in the department of Chemistry and Biochemistry have developed a novel technique of intracellular cargo delivery using nanovolcanos with high efficiency and cell viability.BACKGROUND: Intracellular cargo delivery facilitates cellular reprogramming and development of next generation gene and cellular therapies....

Published: 7/19/2023 | Inventor(s): Paul Weiss, Hsian-Rong Tseng, Qing Yang, Xiaobin Xu, Shuang Hou, Steven Jonas

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Drug Delivery, Gene Therapy, Other Polymers

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Other Polymers, Chemical > Industrial & Bulk Chemicals, Therapeutics > Gene Therapy And Editing

2018-436 GUIDED MAGNETIC NANOSPEARS FOR TARGETED AND HIGH-THROUGHPUT INTRACELLULAR DELIVERY

Guided Magnetic Nanospears For Targeted And High-Throughput Intracellular DeliverySUMMARYUCLA researchers in the Department of Chemistry & Biochemistry and Department of Molecular & Medical Pharmacology have developed novel magnetic nanostructures that can be used to carry and/or deliver biomolecular cargo intracellularly to cells.BACKGROUNDCurrent...

Published: 7/19/2023 | Inventor(s): Steven Jonas, Hsian-Rong Tseng, Shuang Hou, Paul Weiss

Keywords(s): Drug Delivery, Life Science Research Tools, Nanoparticles, Other Reagents

Category(s): Life Science Research Tools, Life Science Research Tools > Other Reagents, Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles

Phenotypic Profiling Of Hepatocellular Carcinoma Circulating Tumor Cells For Treatment Selection

SummaryResearchers in the UCLA Departments of Surgery and Molecular and Medical Pharmacology have developed a novel blood-based assay that can capture and characterize circulating tumor cells indicative of both early- and late-staged hepatocellular carcinoma (HCC).BackgroundHepatocellular carcinoma (HCC) is the fifth most common type of cancer, the...

Published: 7/19/2023 | Inventor(s): Hsian-Rong Tseng, Shuang Hou, Vatche Agopian

Keywords(s): Diagnostic Markers & Platforms, Life Science Research Tools, Oncology, Targets And Assays

Category(s): Life Science Research Tools, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Therapeutics > Oncology

Single Circulating Tumor Cell Isolation Using Laser Microdissection And A Polymer Enrichment Assay

SummaryUCLA researchers in the department of Molecular and Medical Pharmacology have developed a novel matrix polymer capture system of circulating tumor cells that preserves biomolecular integrity through laser microdissection for the early detection of metastatic cancer.BackgroundThe most common causes of cancer related deaths occur through the metastases...

Published: 7/19/2023 | Inventor(s): Hsian-Rong Tseng, Mitch Garcia, Libo Zhao, Shuang Hou, Min Song, Tom Lee, Daniel Wang, Bo Tao

Keywords(s): Diagnostic Markers & Platforms, Life Science Research Tools, Microfluidics And Mem's, Oncology

Category(s): Life Science Research Tools, Diagnostic Markers, Life Science Research Tools > Microfluidics And Mems, Therapeutics > Oncology

2013-052 Capture And Stimulated Release Of Circulating Tumor Cells On Polymer Grafted Silicon Nanostructures

SUMMARYUCLA researchers in the department of Molecular and Medical Pharmacology have developed a novel capture system of circulating tumor cells for the early detection of metastatic cancer.BACKGROUNDThe number of cancer related deaths in the U.S. is reported to continue growing in the next decade. A large proportion of these cases, begin as a local...

Published: 7/19/2023 | Inventor(s): Hsian-Rong Tseng, Shuang Hou, Libo Zhao, Hsiao-Hua Yu, Shyh-Chyang Luo, Haichao Zhao

Keywords(s): Diagnostic Markers & Platforms, Life Science Research Tools, Microfluidics And Mem's, Oncology

Category(s): Life Science Research Tools, Diagnostic Markers, Life Science Research Tools > Microfluidics And Mems, Therapeutics > Oncology