Search Results - timothy+deming

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2007-574 Process for Creating Stable Double Emulsions

SUMMARYUCLA Researchers in the Departments of Chemistry, Physics, and Bioengineering have developed a process for creating double emulsions (droplets within droplets) for applications in pharmaceuticals, drug delivery, cosmetics, and personal care products. By contrast to more common double emulsions that have microscale droplet sizes, UCLA researchers...

Published: 7/19/2023 | Inventor(s): Thomas Mason, Timothy Deming, Connie Wilking, Sara Harvey, Jarrod Hanson

Keywords(s):

Category(s): Materials > Functional Materials

2019-238 MIXTURES OF SYNTHETIC COPOLYPEPTIDE HYDROGELS

UCLA researchers in the Department of Bioengineering have developed a novel polypeptide-based hydrogel mixture that offers a large degree of biocompatibility and biodegradability while also offering the ability to tune mechanical properties. Specifically, these compositions allow for high hydrogel stiffness at low polymer concentrations, while retaining...

Published: 7/19/2023 | Inventor(s): Timothy Deming

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Drug Delivery, Other Polymers

Category(s): Platforms > Drug Delivery > Other Polymers, Chemical > Industrial & Bulk Chemicals

2015-612 PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS VIA RING OPENING REACTIONS

INTRO SENTENCE: UCLA researchers in the Department of Bioengineering have developed a simple approach to modify polypeptides and proteins.BACKGROUND: Functionalized polypeptides and proteins are useful as drug delivery vehicles, bioconjugates and novel ligands. However, synthesis of complex polypeptides with defined post-polymerization modifications...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Eric Gharakhanian

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Drug Delivery, Peptide Base

Category(s): Chemical > Synthesis, Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base, Chemical > Industrial & Bulk Chemicals

2016-579 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES

Preparation Of Functional Homocysteine Residues In Polypeptides And PeptidesSUMMARYUCLA researchers in the Department of Bioengineering and Department of Chemistry & Biochemistry have developed a novel method for efficient, chemoselective transformation of methionines in peptides and polypeptides into stable, functional homocysteine derivatives....

Published: 7/19/2023 | Inventor(s): Timothy Deming, Eric Gharakhanian

Keywords(s):

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base

Chemoselective Side-Chain Modifications Of Methionine-Containing Elastin-Like Polypeptides

SummaryUCLA researchers in the Department of Bioengineering and Department of Chemistry & Biochemistry have developed a novel method for the introduction of various functional groups onto recombinant elastin-like polypeptides (ELPs), creating new compositions of ELPs that may be used for medical therapeutic or diagnostic applications.BackgroundRecombinant...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Sebastien Le-Commandoux, Elizabeth Garanger

Keywords(s): Drug Delivery, Peptide Base

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base

Preparation Of Functionalized Polypeptides, Peptides, And Proteins By Alkylation Of Thioether Groups

SummaryUCLA researchers in the Departments of Chemistry, Physics, and Bioengineering, led by Dr. Tim Deming of the Bioengineering Department, have developed new methods for adding different functional groups on polypeptides. The UCLA researchers have used this method to create a platform to create and modify nanoscale vesicles and hydrogels for use...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Jessica Kramer

Keywords(s): Animal Imaging, Drug Delivery, Life Science Research Tools, Medical Devices and Materials, Medical Imaging, Nanoparticles, Other, Surgical Tools

Category(s): Life Science Research Tools, Life Science Research Tools > Animal Imaging, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Surgical Tools, Platforms > Drug Delivery, Platforms > Drug Delivery > Nanoparticles

Amphiphilic Derivatives Of Thioether Containing Block Copolypeptides

SummaryUCLA researchers in the Department of Bioengineering have developed a new method to generate amphiphilic block copolypeptides.BackgroundBlock copolymers with amphiphilic character can self-assemble into a variety of micellar structures, including spherical micelles, rodlike micelles, or vesicles. These structures have utility in drug delivery,...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Jessica Kramer, April Rodriguez

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Drug Delivery, Nucleic Acids, Other Polymers

Category(s): Diagnostic Markers, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms > Drug Delivery > Nucleic Acids, Platforms > Drug Delivery > Other Polymers

Use Of Non-Ionic Copolypeptide Hydrogels For Cell Suspension And Cell And Molecule Delivery

SummaryUCLA researchers in the Departments of Bioengineering, Chemistry and Biochemistry, and Neurobiology have developed novel copolypeptide hydrogel formulations for the delivery of cells and molecules to locations throughout the body, including the central nervous system.BackgroundCentral nervous system (CNS) disorders, commonly caused by trauma,...

Published: 7/19/2023 | Inventor(s): Timothy Deming, Michael Sofroniew, Shanshan Zhang

Keywords(s): Cns, Drug Delivery, Medical Devices and Materials, Peptide Base

Category(s): Medical Devices, Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base, Therapeutics > CNS and Neurology