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2005-010 MUTATED RENILLA LUCIFERASE FOR HIGHER LIGHT OUTPUT AND ALTERED STABILITY
A Novel Renilla-Derived Luciferase with Enhanced Activity and StabilitySUMMARYUCLA researchers in the Department of Molecular and Medical Pharmacology have developed a novel luciferase variant with enhanced stability and activity.BACKGROUNDLuciferase proteins first derived from firefly are indispensable in biological research. They are used for in vivo...
Published: 7/19/2023
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Inventor(s):
Anna Wu
,
Andreas Loening
,
Sanjiv Gambhir
Keywords(s):
Animal Imaging
,
Life Science Research Tools
,
Medical Imaging
,
Microscopy And Imaging
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Microscopy And Imaging
,
Life Science Research Tools > Animal Imaging
,
Medical Devices > Medical Imaging
2013-185 FULLY HUMAN ANTIBODIES AND FRAGMENTS RECOGNIZING HUMAN C-MET
Fully Human Antibodies and Fragments Recognizing c-MetSUMMARYUCLA researchers in the Department of Molecular and Medical Pharmacology have developed several novel recognition sequences against the human oncogene c-MET. These unique sequences are the basic building blocks used to make intact human antibodies and antibody fragments that can be conjugated...
Published: 3/8/2024
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Inventor(s):
Anna Wu
,
Keyu Li
Keywords(s):
Category(s):
Therapeutics
,
Therapeutics > Oncology
2017-645 HUMANIZED ANTIBODIES TO THE EXTRACELLULAR DOMAINS OF HUMAN N-CADHERIN
UCLA researchers in the Department of Molecular and Medical Pharmacology have developed humanized antibody therapies for invasive prostate and bladder cancers that express N-cadherin.BACKGROUNDProstate cancer is the second leading cause of cancer death among men in the United States (National Cancer Institute). Unfortunately, systemic therapies such...
Published: 3/8/2024
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Inventor(s):
Anna Wu
,
Robert Reiter
,
Kirstin Zettlitz
Keywords(s):
Antibodies
,
Antibody Delivery Platforms
,
Diagnostic Markers & Platforms
,
Drug Delivery
,
Gastroenterology & Digestive Disease
,
Life Science Research Tools
,
Nucleic Acids
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Antibodies
,
Diagnostic Markers
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Antibody Delivery Platforms
,
Therapeutics
,
Therapeutics > Gastroenterology
,
Platforms > Drug Delivery > Nucleic Acids