2020-395 Biomarkers for Treatment of Post-Traumatic Stress Disorder Using Closed-Loop Neuromodulation


UCLA researches in the Department of Neurosurgery have developed a novel method for the diagnosis and treatment of Post-Traumatic Stress Disorder.


Post-traumatic stress disorder is a mental health condition resulting from a patient having a heightened sensed of fear after encountering a traumatic scenario. It is most often characterized by a hypervigilance response and an inability to extinguish fear. Current treatments for this disorder are limited to psychological therapy and several medications. As such, there is a need for treatments that can affect the resulting electrical imbalances in the brain and help to alleviate this debilitating trauma.


Researchers at UCLA have developed a method for the diagnosis and treatment of patients experiencing post-traumatic stress disorder. The method directly detects brain activity, allowing for quantifiable diagnosis of the disorder and for corresponding treatments of these specific regions. As such, UCLA researchers have developed a treatment that when applied synergistically with known effective psychological therapy techniques can enhance treatments for post-traumatic stress disorder.


  • Treatments for Post-Traumatic Stress Disorder
  • Possible future treatments for other neurological disorders


  • Allows for targeted and trackable treatment of Post-Traumatic Stress Disorder
  • Alternative treatment compared to standard practices


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Megha Patel
Business Development Officer
Jean Philippe Langevin