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Synthesis of Heteroatom Containing Polycyclic Aromatic Hydrocarbons (Case No. 2019-232)

Summary: UCLA researchers in the Department of Chemistry & Biochemistry have developed an approach for synthesizing nitrogen-containing polycyclic aromatic hydrocarbons with high yield. Background: There is a widespread use of nitrogen-containing heterocyclic compounds in small-molecule pharmaceutical intermediates. There is also a growing need...

Published: 11/18/2024 | Inventor(s): Neil Garg, Evan Darzi, Joyann Barber

Keywords(s): Catalysts, Chemical Manufacturing & Industrial/Bulk Chemicals, Displays, Electronics & Semiconductors, Energy & Water, Optics, Photonics

Category(s): Electrical > Electronics & Semiconductors, Optics & Photonics, Materials > Semiconducting Materials, Energy & Environment > Energy Generation > Solar, Chemical > Industrial & Bulk Chemicals, Chemical > Synthesis, Electrical > Displays

2011-132 Enhanced Strength Carbon Nanotube Yarns

SUMMARYResearchers at the UCLA Department of Engineering have developed novel carbon nanotube/resin composite material that dramatically enhances strength and toughness of carbon nanotubes.BACKGROUNDCarbon nanotubes (CNTs) are the strongest and stiffest materials yet discovered in terms of tensile strength and elastic modulus, compared to steel and...

Published: 7/19/2023 | Inventor(s): Larry Carlson

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Construction Materials

Category(s): Materials > Composite Materials, Chemical > Industrial & Bulk Chemicals

2020-478 CONVERSION OF HETEROCYCLES TO NOVEL POLYMERS CONTAINING STRAINED FUNCTIONALITY AND CAPACITY FOR POST-POLYMERIZATION MODIFICATION

UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel method for the conversion of Dewar heterocycles to versatile monomers with capacity for post-polymerization chemistry. BACKGROUND: Post-polymerization modifications are crucial in the development of synthetic materials for electronic, biomedical, and feedstock...

Published: 7/19/2023 | Inventor(s): Hosea Nelson

Keywords(s): Catalysts, Chemical, Chemical Manufacturing & Industrial/Bulk Chemicals, Functional Materials

Category(s): Chemical > Catalysts, Chemical > Polymers, Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals

2019-866 METHODS FOR IMPROVING THE TISSUE SEALING PROPERTIES OF HYDROGELS AND THE USE THEREOF

UCLA researchers in the Department of Bioengineering have optimized the sealing properties of naturally derived biopolymers, without altering their other attractive abilities like biodegradation.BACKGROUND: A significant number of emergency room cases consist of wound-related injuries. While the body is particularly adapted to treat various types of...

Published: 11/15/2024 | Inventor(s): Ali Khademhosseini, Nasim Annabi, Amir Sheikhi

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Structures

Category(s): Chemical > Industrial & Bulk Chemicals

2014-054 Gas Fill-Up Process System and Methodology with Minimum and/or No Cooling

Gas Fill-Up Process System and Methodology with Minimal or No CoolingBACKGROUNDFuel cell electric vehicles (FCEVs) are projected by some industry analysts to become the fastest-growing segment of the auto market. These vehicles use hydrogen gas as fuel, have zero tailpipe emissions, and can be refueled in minutes, compared to the hours required for...

Published: 7/19/2023 | Inventor(s): Vasilios Manousiouthakis, Fernando Olmos

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Energy & Water, Fluid Dynamics

Category(s): Energy & Environment > Energy Storage > Batteries, Chemical > Industrial & Bulk Chemicals, Energy & Environment > Energy Storage > Gas Storage

2020-388 Spectrally Selective Thermal Radiators for Cooling of Vertical or Horizontal Surfaces with Limited View of the Sky

SUMMARY UCLA researchers in the Department of Materials Science and Engineering have developed a passive radiative cooling design for building surfaces that have a limited view of the sky by using spectrally selective thermal radiating materials. BACKGROUND Passive radiative cooling (PRC), a process where objects on Earth radiate heat into outer...

Published: 8/16/2024 | Inventor(s): Jyotirmoy Mandal, Pattabhi "Aaswath" Raman

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Heat Transfer, Materials, Mechanical Systems

Category(s): Mechanical > Mechanical Systems, Chemical > Industrial & Bulk Chemicals, Energy & Environment > Thermal

2019-641 LATE TRANSITION METAL MEDIATED BASE PAIRS AND APPLICATIONS IN BIOTECHNOLOGY AND SYNTHESIS

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method of metal-mediated base pair stabilization in vivo, with additional applications in the detection of small nucleic acids and regulation of transition metal catalysis. BACKGROUND:Recent studies of the interactions between transition metals and DNA have led...

Published: 7/19/2023 | Inventor(s): Hosea Nelson

Keywords(s): Catalysts, Chemical Manufacturing & Industrial/Bulk Chemicals, Inflammatory Diseases, Life Science Research Tools, Other, Therapeutics & Vaccines

Category(s): Chemical > Synthesis, Therapeutics > Inflammation And Inflammatory Diseases

2019-958 SELECTIVE HDAC INHIBITORS

UCLA researchers in the Department of Chemistry and Biochemistry have synthesized a series of novel hydroxamic acids and derivatives as selective histone deacetylase (HDAC) inhibitors from simple starting materials.BACKGROUND:Histone deacetylase (HDAC) inhibitors are chemical compounds that regulates gene expression by inhibiting histone deacetylases....

Published: 7/19/2023 | Inventor(s): Michael Jung, Jonghoon Kim

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Cns, Gene Editing Systems, Gene Therapy, Infectious Diseases, Inflammatory Diseases, Therapeutics & Vaccines

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Infectious Diseases, Therapeutics > Gene Therapy And Editing, Therapeutics > Inflammation And Inflammatory Diseases, Chemical > Industrial & Bulk Chemicals

2019-238 MIXTURES OF SYNTHETIC COPOLYPEPTIDE HYDROGELS

UCLA researchers in the Department of Bioengineering have developed a novel polypeptide-based hydrogel mixture that offers a large degree of biocompatibility and biodegradability while also offering the ability to tune mechanical properties. Specifically, these compositions allow for high hydrogel stiffness at low polymer concentrations, while retaining...

Published: 7/19/2023 | Inventor(s): Timothy Deming

Keywords(s): Chemical Manufacturing & Industrial/Bulk Chemicals, Drug Delivery, Other Polymers

Category(s): Platforms > Drug Delivery > Other Polymers, Chemical > Industrial & Bulk Chemicals

2020-148 METHODS FOR PRODUCING D-TRYPTOPHAN AND SUBSTITUTE D-TRYPTOPHANS

UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel biochemical synthesis process to produce D-Tryptophan at high yield and 98% enantiomeric excess with peptide synthetase IvoA from recombinant yeast.BACKGROUND:D-tryptophans are important building blocks of many peptide-based pharmaceuticals. The common...

Published: 7/19/2023 | Inventor(s): Yi Tang, Yang Hai

Keywords(s): Catalysts, Chemical Manufacturing & Industrial/Bulk Chemicals, Life Science Research Tools, Other Reagents

Category(s): Life Science Research Tools > Other Reagents, Chemical > Synthesis, Chemical > Industrial & Bulk Chemicals

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