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An Alternative T Cell Redirecting Bispecific Antibody Against Human Cytomegalovirus (UCLA Case No. 2024-198)
UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have created a novel T cell redirecting bispecific antibody (TRBA) for treatment of cytomegalovirus (CMV) infection. BACKGROUND: The
human cytomegalovirus (CMV)
has a seroprevalence of about 60% in the USA and nearly 100% of the population in some parts of the world....
Published: 11/15/2024
|
Inventor(s):
Otto Yang
Keywords(s):
Anti-CD3 antibodies
,
Bispecific antibodies
,
CD8 T cells
,
Human cytomegalovirus (CMV)
,
immunocompromised patients
,
Immunotherapy
,
Lymphocytes
,
T cell redirecting bispecific antibody (TRBA)
,
Transplant
,
Viral infection
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Immunology And Immunotherapy
A T-Cell Redirecting Bispecific Antibody Against Human Cytomegalovirus (UCLA Case No. 2023-020)
UCLA researchers at the Departments of Medicine and Microbiology Immunology and Molecular Genetics have developed a novel bispecific antibody-based immunotherapy strategy for the treatment of Cytomegalovirus infections. BACKGROUND: The
human cytomegalovirus (CMV)
is a widespread virus estimated to infect 60% of American adults and nearly 100% of...
Published: 11/15/2024
|
Inventor(s):
Otto Yang
Keywords(s):
Anti-CD3 antibodies
,
Bispecific antibodies
,
CD8 T cells
,
Human cytomegalovirus (CMV)
,
Immunotherapy
,
Lymphocytes
,
T cell redirecting bispecific antibody (TRBA)
,
Viral infection
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Immunology And Immunotherapy