Search Results - transplant

3 Results

Sort By:

Intrastromal Lamellar Keratoprosthesis (Artificial Cornea) (Case No. 2025-177)

Summary: UCLA researchers in the Department of Ophthalmology have developed an intrastromal artificial cornea implant designed to enhance biointegration and effectively restore vision. Background: Corneal opacities are among the top five causes of blindness worldwide. For patients who are not candidates for conventional corneal transplantation, keratoprosthesis...

Published: 6/16/2025 | Inventor(s): Seyed Reza Ghaffari Dehkharghani, Anthony Aldave

Keywords(s): Biologic Medical Product, Biomedical Engineering, biomedical implantation, biomedical sensors, diseases of the eye, eye disease, eye motion, eye movement disorders, Eye Surgery, eye tracking, Glaucoma, macular corneal dystrophy, Macular Degeneration, Medical Device, Medical Imaging Eyepiece, on-eyelid sensor, Ophthalmic antibiotics, Ophthalmology, Other Polymers, Polymers, Prosthetics, Transplant, Transplant Rejection, transplant surgery

Category(s): Medical Devices, Medical Devices > Surgical Tools, Therapeutics > Ophthalmology

An Alternative T Cell Redirecting Bispecific Antibody Against Human Cytomegalovirus (UCLA Case No. 2024-198)

UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have created a novel T cell redirecting bispecific antibody (TRBA) for treatment of cytomegalovirus (CMV) infection. BACKGROUND: The human cytomegalovirus (CMV) has a seroprevalence of about 60% in the USA and nearly 100% of the population in some parts of the world....

Published: 2/14/2025 | Inventor(s): Otto Yang

Keywords(s): Anti-CD3 antibodies, Bispecific antibodies, CD8 T cells, Human cytomegalovirus (CMV), immunocompromised patients, Immunotherapy, Lymphocytes, T cell redirecting bispecific antibody (TRBA), Transplant, Viral infection

Category(s): Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy

Method for Combined Conditioning and Chemoselection in a Single Cycle (UCLA Case No. 2011-478)

SUMMARY: Researchers at UCLA have developed a highly-efficient technique to engraft and select hematopoietic stem cells directly inside a patient. The invention will improve the fidelity of stem cell transplantations and reduce toxic side effects on patients. BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a mainstay of treatment for...

Published: 2/14/2025 | Inventor(s): Gay Crooks, Robert Schiestl, Katrin Hacke, Akos Szakmary

Keywords(s): blood cancers, Cancer stem cells, Hematopoietic stem cell transplantation, hematopoietic stem cells, lymphatic cancer, stem cell transplantations, Transplant

Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Transplant