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Targeting Plasma Extracellular Vesicles as Therapy for Severe Bacterial Pneumonia (UCLA Case No. 2025-274)

UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have identified a novel method of targeting plasma extracellular vesicles to help suppress inflammation and infection during severe bacterial pneumonia. BACKGROUND: Direct and indirect lung injury such as through pneumonia or following abdominal infections can lead to...

Published: 6/27/2025 | Inventor(s): Jae Woo Lee

Keywords(s):

Category(s): Therapeutics > Infectious Diseases, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Respiratory And Pulmonary

Use of Endogenous Plasma Extracellular Vesicles as an Adjuvant Therapeutic for Pneumonia (UCLA Case No. 2025-236)

UCLA researchers in the Department of Anesthesiology & Perioperative Medicine have developed a novel therapeutic approach using human extracellular vesicles (EVs) to block harmful effects of bacterial outer membrane vesicles (OMVs) in Pseudomonas aeruginosa pneumonia. This strategy aims to reduce inflammation, disrupt bacterial communication, and...

Published: 6/27/2025 | Inventor(s): Jae Woo Lee

Keywords(s):

Category(s): Therapeutics > Respiratory And Pulmonary, Therapeutics > Infectious Diseases