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Molecular Regulation of Stroke-Resistant Neurons (UCLA Case No. 2020-937)
Researchers in the Department of Neurology at UCLA have identified pharmacologic compounds capable of crossing the blood brain barrier that dramatically promote neurite outgrowth after stroke, thereby promoting recovery. Background: A stroke occurs when the blood supply of oxygen is interrupted to the brain, preventing brain tissue from receiving oxygen...
Published: 10/8/2025
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Inventor(s):
Jason Hinman
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology
Novel MARK4 Inhibitors for Neurodegenerative Disorders (UCLA Case No. 2021-321)
UCLA researchers in the Department of Neurology have developed highly selective inhibitors of MARK4, aiming to revolutionize the treatment landscape for cancer and neurodegenerative disease through precise molecular targeting. BACKGROUND: MARK4 (Microtubule Affinity-Regulating Kinase 4) is a serine/threonine kinase from the AMP-activated protein...
Published: 9/10/2025
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Inventor(s):
Varghese John
,
Jason Hinman
,
Jesus Campagna
Keywords(s):
Category(s):
Therapeutics > CNS and Neurology