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DNA Methylation-Based Algorithm to Diagnose Irritable Bowel Syndrome and Other GI Conditions (UCLA Case No. 2022-229)
UCLA researchers in the Department of Gastroenterology have developed a DNA methylation-based algorithm to diagnose irritable bowel syndrome and other GI conditions. Blood-based genome-wide DNA methylation profiles have been utilized to develop a reliable test to diagnose irritable bowel syndrome (IBS) versus inflammatory bowel disease (IBD), celiac...
Published: 9/11/2025
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Inventor(s):
Lin Chang
,
Swapna Joshi
Keywords(s):
Category(s):
Therapeutics > Gastroenterology
,
Platforms > Diagnostic Platform Technologies
Epigenetic Profile-Based Biomarkers for Irritable Bowel Syndrome (UCLA Case No. 2018-578)
SummaryUCLA researchers from the Vatche and Tamar Manoukian Division of Digestive Diseases have discovered an innovative approach to diagnose irritable bowel syndrome. This method uses a set of epigenetic profiles as biomarkers and is highly sensitive compared to conventional diagnostic methodologies. BackgroundIrritable bowel syndrome (IBS) affects...
Published: 7/17/2025
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Inventor(s):
Lin Chang
,
Swapnali Joshi
Keywords(s):
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Gastroenterology & Digestive Disease
Category(s):
Diagnostic Markers
,
Platforms > Diagnostic Platform Technologies
,
Therapeutics > Gastroenterology