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2018-856 AN APPROACH FOR TARGETED CONDITIONING FOR T CELL TRANSPLANTS

UCLA researchers in the Departments of Microbiology, Immunology, and Molecular Genetics have identified a pre-conditioning reagent for Adoptive Cell Transfer (ACT). The identified reagent specifically ablates T-cells making room for infused cells to engraft and has negligible toxicities compared to traditional conditioning therapies that affect all...

Published: 9/5/2023 | Inventor(s): Irvin S.Y. Chen, Sanggu Kim, Masakazu Kamata, Gajendra Suryawanshi, Robert Donahue

Keywords(s): Immunotherapy, Therapeutics & Vaccines

Category(s): Therapeutics > Immunology And Immunotherapy

2018-749 A METHOD TO DISTINGUISH DIFFERENT RETROVIRAL VECTORS DURING INTEGRATION SITE ANALYSIS

UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed a novel gene therapy vector identifying method, capable of screening toxicities of combination therapies.TITLE: A Method to Distinguish Different Retroviral Vectors During Integration Site Analysis BACKGROUND: Many diseases originate from defective...

Published: 7/19/2023 | Inventor(s): Irvin S.Y. Chen, Gajendra Suryawanshi, Sanggu Kim

Keywords(s): Gene Editing Systems, Gene Therapy, Life Science Research Tools, Plasmids / Vectors, Therapeutics & Vaccines

Category(s): Life Science Research Tools, Life Science Research Tools > Plasmids/Vectors, Therapeutics, Therapeutics > Gene Therapy And Editing