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2004-598 Statins as Treatment for Cognitive Dysfunction Associated with RASopathies

Summary Professor Alcino Silva and colleagues at the UCLA department of Neurobiology have repurposed HMG-CoA reductase inhibitors (statins) to reverse cognitive dysfunction associated with RASopathies, such as neurofibromatosis type 1 and Noonan syndrome. Background RASopathies comprise a group of developmental syndromes arising from germline mutations...

Published: 7/19/2023 | Inventor(s): Alcino Silva, Steven Kushner, Weidong Li, Yijun Cui

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Category(s): Therapeutics > CNS and Neurology