Search Results - synthetic+biology

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Methods for Building RNA Organelles in Vitro (UCLA Case No. 2023-286)

UCLA researchers from the Department of Bioengineering have developed artificial RNA sequences that can form condensates in vitro, allowing customization of cellular function in membrane-less organelles. BACKGROUND: RNA condensates are intracellular membrane-less compartments formed by phase separation, involving RNA and proteins. These RNA condensates...

Published: 5/12/2025 | Inventor(s): Elisa Franco

Keywords(s): Nanotechnology, RNA, synthetic biology

Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools > Plasmids/Vectors

Synthetic Exosomes (SE) for CNS Delivery of CRISPR for Gene Editing in Brain Disorders (UCLA Case No. 2021-363)

UCLA researchers from the Department of Neurology have developed synthetic exosomes, a novel delivery technology capable of transporting gene-editing tools and therapeutics across the blood-brain barrier, with successful applications in repairing Alzheimer’s-related mutations and delivering proteins, antibodies, and drugs. BACKGROUND: The emergence...

Published: 2/18/2025 | Inventor(s): Varghese John

Keywords(s): Alzheimers disease, CRISPR, delivery system, exosome, Nanotechnology, nanovesicles, synthetic biology

Category(s): Life Science Research Tools > Microfluidics And Mems, Materials > Nanotechnology, Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Therapeutics > CNS and Neurology