Search Results - therapeutics+%3e+transplant

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Method for Combined Conditioning and Chemoselection in a Single Cycle (UCLA Case No. 2011-478)

SUMMARY: Researchers at UCLA have developed a highly-efficient technique to engraft and select hematopoietic stem cells directly inside a patient. The invention will improve the fidelity of stem cell transplantations and reduce toxic side effects on patients. BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a mainstay of treatment for...

Published: 2/16/2024 | Inventor(s): Gay Crooks, Robert Schiestl, Katrin Hacke, Akos Szakmary

Keywords(s): blood cancers, Cancer stem cells, Hematopoietic stem cell transplantation, hematopoietic stem cells, lymphatic cancer, stem cell transplantations, Transplant

Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Transplant

2011-896 Protein Biomarkers for Immune Assessment and Prediction of Transplant Rejection

Background Current diagnostic methods of renal allograft rejection are neither sensitive, nor specific. Needle biopsies are invasive and associated with patient morbidity. It is thus desirable to develop noninvasive tests to predict and diagnose rejection. Innovation UCLA researchers have identified a number of proteins present in human plasma associated...

Published: 7/19/2023 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Transplant

2008-369 Fungal Immunosuppressive Compounds

Summary UCLA inventors have discovered a novel compound from a fungus that would have broad applicability for the treatment of human autoimmune diseases and transplantation rejection. Background Endophytes, microorganisms that reside in the tissues of living plants, are relatively unstudied and potential sources of novel natural products for exploitation...

Published: 9/20/2023 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Transplant

2012-292 Organ Resuscitation Solution & System for Enhanced Liver Transplantation

Summary Background Liver organs suffer a tremendous degree of ischemia and reperfusion injury (IRI) during transplantation. The injury stems from the interruption of blood flow and depletion of nutrients to the organ in the period between donor organ procurement, preservation and transplantation into the recipient. Cell injury or death and metabolic...

Published: 7/19/2023 | Inventor(s):

Keywords(s):

Category(s): Therapeutics > Transplant