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2019-523 PROTEIN KINASE INHIBITORS WHICH ALSO TARGET DIHYDROOROTATE DEHYDROGENASE

SUMMARY: Researchers from UCLA’s Department of Molecular and Medicinal Pharmacology have discovered two protein kinase inhibitors that effectively inhibit dihydroorotate dehydrogenase, an enzyme linked to cancer progression. BACKGROUND: During the progression of cancer, normal healthy cells undergo mutation that converts normal cell phenotypes...

Published: 9/5/2023 | Inventor(s): Caius Radu, Evan Abt, Ethan Rosser

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Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Oncology > Oncology (Small Molecules)