Search Results - therapeutics

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XR Platform for Personalized Neurological Rehabilitation and Diagnostics (Case No. 2025-99L)

Summary: UCLA researchers in the Department of Neurology have developed a novel AI-driven mixed reality headset for precision stroke rehabilitation. Background: Stroke is a leading cause of long-term motor disability, often requiring prolonged and intensive rehabilitation to restore motor function. Current methods for evaluating motor impairments...

Published: 5/13/2026 | Inventor(s): Ahmet Arac, Nicolas Jeong Lee, John Krakauer

Keywords(s):

Category(s): Electrical, Electrical > Displays, Electrical > Visual Computing, Electrical > Visual Computing > AR/VR/Mixed Reality, Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > Musculoskeletal Disease, Therapeutics > Psychiatry And Mental Health

Linking the Gap Between Traumatic Brain Injuries & Cognitive Impairments Through the Creation of Machine Learning Based Diagnostic & Prognostic Clinic (Case No. 2026-251)

Summary: UCLA researchers have developed a machine learning-based clinical decision support tool that predicts patient-specific cognitive impairments following traumatic brain injury (TBI) using neuroimaging and multimodal clinical data. The software leverages MRI-derived structural brain information to generate individualized diagnostic and prognostic...

Published: 5/1/2026 | Inventor(s): Sonya Ashikyan, Martin Monti, Jeffrey Chiang

Keywords(s):

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Bioinformatics, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > CT, Medical Devices > Medical Imaging > MRI, Therapeutics > CNS and Neurology, Therapeutics

Active Electromagnetic Interference Suppression for Magnetic Resonance Imaging-Guided Interventions (Case No. 2026-217)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a software-based active electromagnetic interference suppression solution for real-time MRI-guided interventions. Background: Microwave ablation (MWA) has emerged as the preferred thermal ablation modality for treating non-surgical patients with primary and metastatic...

Published: 4/16/2026 | Inventor(s): Holden Wu, Qing Dai

Keywords(s):

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Lab Equipment, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Mechanical, Mechanical > Instrumentation, Mechanical > Sensors, Electrical, Electrical > Electronics & Semiconductors, Electrical > Signal Processing, Electrical > Instrumentation, Electrical > Imaging

A Wearable Magnetoelastic Patch for Cervical Spines Care (Case No. 2026-076)

Summary: UCLA researchers have developed a soft, wearable magnetoelastic patch designed for real-time, non-invasive monitoring of cervical spine pressure and motion, enabling early detection and personalized care for infants with potential neck or spine disorders. Background: Infant cervical spine injuries present a significant diagnostic challenge...

Published: 2/4/2026 | Inventor(s): Jun Chen

Keywords(s): Neurosurgery/Spine

Category(s): Diagnostic Markers > Pediatrics, Electrical > Electronics & Semiconductors, Electrical > Flexible Electronics, Electrical > Sensors, Materials > Fabrication Technologies, Mechanical > Sensors, Medical Devices > Monitoring And Recording Systems, Software & Algorithms > AI Algorithms, Therapeutics

Mental Health Functional Movement Scale (MH-FMS) (Case No. 2025-021)

Summary: UCLA researchers in the Department of Psychiatry and Behavioral Sciences have created a novel assessment platform that objectively measures how the brain, body, and autonomic nervous system respond to stress and regulate emotion during real-time movement. By integrating a shear-stress–based neurovascular framework with a polyvagal-informed...

Published: 12/17/2025 | Inventor(s): Naser Ahmadi, Mike Ramirez, Julien Pineau

Keywords(s): blood flow management, Cardiovascular, cellular, clinical care methodology, clinical decision support, Clinical decision support system, clinical mental health, Clinical tool, exercise physiology, Hemodynamics, Mental health, neurobehavioral impairment, Neurocognitive, Neurocognitive Scientific Method, neurodevelopment, neurological disorders, Neuropsychological Test, neuroscience, Neurostimulation, Psychiatry / Mental Health

Category(s): Diagnostic Markers, Life Science Research Tools, Medical Devices, Medical Devices > Hospital Systems, Therapeutics, Therapeutics > Psychiatry And Mental Health

Broad-Band Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Neuropsychiatric Disorders (Case No. 2025-99J)

Summary: Researchers in UCLA's Semel Institute and Department of Psychiatry have developed an innovative approach to treating depression by optimizing repetitive Transcranial Magnetic Stimulation (rTMS), improving its effectiveness for the treatment of Major Depressive Disorder (MDD) and possibly diseases of the mind and brain. Background: Depression...

Published: 10/16/2025 | Inventor(s): Andrew Leuchter, Juliana Corlier, Thomas Valles

Keywords(s): Bioelectromagnetics, Brain, Deep Brain Stimulation, Electrical Brain Stimulation, energy-efficient, frequency modulation, Magnetic Field, Medical Device, medication efficacy, neural information, neural network, neural networks, neural signals, neural stimulation, neurobehavioral impairment, Neurocognitive, neurological disorders, Neuromodulation, Neuron, neurons, neuroscience, Neurostimulation, pulsed load modulation, therapy, treatment efficacy

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Life Science Research Tools, Therapeutics > CNS and Neurology, Therapeutics

Balloon Catheter for Thermal Ablation Protection (Case No. 2024-210)

Summary UCLA researchers have developed a novel planar balloon catheter that reliably separates and protects organs during thermal ablation procedures. By creating a sheet-like thermal barrier, the device mitigates unintended injury to nearby healthy tissues—particularly the stomach and bowel—thereby enabling safer and more effective treatment...

Published: 4/3/2026 | Inventor(s): David Lu

Keywords(s): catheter, Catheterization, Swan-Ganz catheter

Category(s): Medical Devices, Medical Devices > Surgical Tools, Therapeutics > Oncology, Therapeutics > Renal, Therapeutics

Self-Amplifying RNA Form of a Constitutively-Active Sting Protein for Enhancing T-Cell Response to Antigen-Presenting Cells (UCLA Case No. 2020-771)

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method for delivering RNA to induce an immune response to cancer cells. BACKGROUND: Cancer therapy continues to remain a challenge despite improvements in detection and clinically available therapies. Recently, improvements to this field have been mainly in the...

Published: 10/22/2025 | Inventor(s): William Gelbart

Keywords(s): Adenoviridae

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy, Diagnostic Markers > Targets And Assays

Self-Powered Electrical Stimulation Magnetoelastic Bandage for Accelerated Wound Healing (Case No. 2025-99N)

Reference: UCLA Case No. 2025-99N Please reach out to our office for more information.

Published: 10/10/2025 | Inventor(s): Jun Chen, Kanishk Rai, Song Li, Il Woo Ock, Haochen Nan

Keywords(s):

Category(s): Therapeutics, Therapeutics > Aesthetic Medicine, Materials, Materials > Functional Materials, Materials > Membranes, Electrical, Electrical > Flexible Electronics

Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)

Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...

Published: 4/29/2026 | Inventor(s): Wentai Liu

Keywords(s): algorithmic cancer detection, Bladder Cancer, blood cancers, Brain cancer, Breast Cancer, Cancer, cancer antigen, cancer detection, Cancer Immunotherapy, cancer inhibition, cancer metabolism, Cancer stem cells, cancer target, castration resistant prostate cancer, Chemotherapy, head and neck cancer, lympathic cancers, lymphatic cancer, Mesenchymal Stem Cell Derived Cancer Cells, Neuromodulation, non-small cell lung cancer, Orthotopic cancer models, Pancreatic cancer, prostate cancer, small cell cancer, small cell lung cancer, small cell prostate cancer

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Chemical, Electrical, Therapeutics, Therapeutics > Oncology

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