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2008-541 SMALL MOLECULE INHIBITORS OF GERANYLGERANYLTRANSFERASE-I AND II
Novel Non-Peptidomimetic Prenyltransferase InhibitorsSUMMARYUCLA Researchers in the Department of Chemistry & Biochemistry and School of Medicine have synthesized a series of small molecule therapeutics against GGTase-I and GGTase-II, both of which are critical oncology drug targets.BACKGROUNDThe Ras protein is typically abnormally active in cancer...
Published: 2/14/2025
|
Inventor(s):
Ohyun Kwon
,
Hannah D.G. Fiji
,
Fuyuhiko Tamanoi
,
Masaru Watanabe
Keywords(s):
Oncology
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Oncology