Search Results - heather+christofk

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KHK Inhibitors as Agents for the Treatment of Cancer and Metabolic Syndrome (UCLA Case No. 2021-222)

UCLA researchers in the Department of Chemistry and Biochemistry have synthesized novel KHK inhibitors that can result in anticancer drugs targeting cancer metabolism. BACKGROUND: Fructose is a naturally occurring sugar found in fruits and vegetables, and is an integral part of the human diet. In comparison to its functional isomer, glucose, which...

Published: 3/31/2025 | Inventor(s): Heather Christofk, Michael Jung

Keywords(s): Cancer, cancer metabolism, metabolism, Oncology (Small Molecules, Peptides and Antibodies), small molecules

Category(s): Therapeutics > Oncology, Therapeutics > Metabolism And Endocrinology

2020-940 USE OF MTORC1 INHIBITORS TO TREAT COVID-19

UCLA researchers in the Department of Biological Chemistry have implicated a novel marker in SARS-CoV-2 infection, identifying a novel drug target for therapeutics treating COVID-19.BACKGROUNDSevere acute respiratory syndrome coronavirus-2, or SARS-CoV-2, is the virus responsible for the 2019 global pandemic (COVID-19): which caused hundreds of millions...

Published: 2/14/2025 | Inventor(s): Heather Christofk, Peter Mullen, Vaithilingaraja Arumugaswami

Keywords(s): Therapeutics & Vaccines

Category(s): Therapeutics

Inhibition of Pyruvate Oxidation to Promote Hair Growth

Case 2018-189UCLA researchers in the departments of Molecular, Cell & Developmental Biology and Biological Chemistry have elucidated a novel mechanism by which pyruvate oxidation can be inhibited in order to promote hair growth.BACKGROUNDThe global market for aging-related hair loss will grow to over $1.4 billion by 2020. However, commercially available...

Published: 2/14/2025 | Inventor(s): William Lowry, Heather Christofk

Keywords(s):

Category(s): Therapeutics > Metabolism And Endocrinology