Search Results - small+molecules

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Identification of Small Molecules as Novel Adipogenic Enhancers for Edible Adipose Tissues (Case No. 2024-125)

Summary: UCLA researchers in the Department of Integrative Biology & Physiology have developed a novel small molecule-based approach for enhancing lipid accumulation and adipogenesis in edible adipose tissues for cultured meat production. Background: With the global population expanding rapidly, there is an urgent demand for sustainable protein...

Published: 8/3/2026 | Inventor(s): Amy Rowat, Robert Damoiseaux, Qingwen Xie

Keywords(s): 3D biofabrication, Agbio, Agriculture, Biomaterial, Cell and tissue culture, Cell Culture, Cell Growth, cell proliferation, cell-extracellular matrix (ECM), cellular aggregates, Cellular agriculture, Cellular Differentiation, Confocal Microscopy, Cultured meat, fat quantification, fatty acids, High-Content Screening, High-Throughput Screening, Industrial applications: food processing, fermentation, lipidomics, meat, meat production, nutrition, scaffolds, Screening Libraries, Small molecule screening, small molecules, subcutaneous adipose tissue, Sustainable nutrition, Tissue Engineering

Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools > Screening Libraries, Life Science Research Tools > Cell Lines, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Therapeutics > Agtech And Animal Health, Chemical > Chemical Processing & Manufacturing, Materials > Functional Materials

Analoging and SAR-Based Chemical Approach to Improve the Therapeutic Potency of Small-Molecule Inhibitors of Metastasis (UCLA Case No. 2024-116)

UCLA researchers in the Department of Molecular and Medical Pharmacology have developed an analoging and SAR-based chemical approach to generate novel, safe, and effective small-molecule inhibitors for preventing and treating cancer metastasis. BACKGROUND: The limited understanding of the biological mechanisms underlying metastasis in clear cell renal...

Published: 7/20/2026 | Inventor(s): Lily Wu, Moe Ishihara, Robert Damoiseaux, Stuart Conway

Keywords(s): Cancer, Metastasis, Oncology (Small Molecules, Peptides and Antibodies), Small molecule therapeutics, small molecules

Category(s): Therapeutics > Oncology

Small Molecule Humanin Mimetics and Enhancers That Normalize Neuronal p-AKT as Novel Therapeutics for Alzheimer's Disease (UCLA Case No. 2023-230)

UCLA researchers in the Department of Neurology have discovered novel small molecule humanin mimetics for the treatment of Alzheimer's disease and other chronic conditions with dysregulated p-Akt. BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia accounting for 60-70% of all cases. Nearly 7 million Americans are living...

Published: 7/20/2026 | Inventor(s): Varghese John

Keywords(s): Alzheimers disease, Cardiovascular, Cardiovascular Disease, Dementia, diabetes, mimetics, pAKT signaling, small molecules

Category(s): Therapeutics > CNS and Neurology, Therapeutics > Cardiovascular