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2020-426 PRODRUGS OF PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN
Researchers at UCLA have developed prodrugs of peripherally-acting cannabinoid (PRCBs) receptor agonists for chronic pain relief. BACKGROUND: Cannabinoids are becoming prevalent in chronic pain treatments even though current marketed cannabinoid compounds may cause psychotropic effects or central nervous system (CNS)-mediated side effects. A potential...
Published: 9/5/2023
|
Inventor(s):
Igor Spigelman
,
Alexander Spokoyny
,
Herbert Seltzman
Keywords(s):
Cns
,
Drug Delivery
,
Therapeutics & Vaccines
Category(s):
Platforms > Drug Delivery
,
Therapeutics
,
Therapeutics > CNS and Neurology
2012-715 Peripherally-Acting Cannabinoid Receptor Agonists for Chronic Pain
Peripherally-Acting Cannabinoid Receptor Agonists for Chronic PainSUMMARYResearchers from UCLA and RTI International have developed novel, small molecule agonists at cannabinoid type 1 and type 2 receptors (CB1R and CB2R) that have low blood-brain barrier (BBB) permeability. The compounds represent promising therapeutics for treating chronic pain....
Published: 7/19/2023
|
Inventor(s):
Igor Spigelman
,
Craig Shiner
,
Herbert Seltzman
Keywords(s):
Anesthesiology
,
Cns
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > CNS and Neurology
,
Therapeutics > Critical Care > Anesthesiology