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Targeted Delivery of IFN-gamma Using Antibody Fusion Proteins (UCLA Case No. 2017-543)
UCLA researchers in the Departments of Microbiology, Immunology & Molecular Genetics (MIMG) and Medicine have developed antibody–cytokine fusion proteins that enable the targeted delivery of active interferon-gamma (IFNγ) for cancer treatment. Interferon-gamma (IFNγ), a type II interferon, is a cytokine released by both natural...
Published: 2/26/2024
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Inventor(s):
Sherie Morrison
,
John Timmerman
,
Kham (Ryan) Trinh
Keywords(s):
Antibody Delivery Platforms
,
Drug Delivery
,
Immunotherapy
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Antibody Delivery Platforms
,
Life Science Research Tools
,
Therapeutics > Immunology And Immunotherapy
2018-384 ANTIBODY-INTERFERON FUSION PROTEINS FOR ENHANCING ADOPTIVE T CELL THERAPIES FOR THE TREATMENT OF CANCER
UCLA researchers in the Departments of Medicine and Microbiology, Immunology and Molecular Genetics have developed a novel combination therapy for enhanced efficacy of Adoptive T Cell Therapies (ACT): that could enable the adoption of ACT as an effective means to combat multiple cancer subtypes. BACKGROUND:The clinical relevancy of cancer immunotherapy...
Published: 7/19/2023
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Inventor(s):
John Timmerman
,
Patricia Young
,
Kham (Ryan) Trinh
,
Sherie Morrison
Keywords(s):
Diagnostic Markers & Platforms
,
Oncology
,
Therapeutics & Vaccines
Category(s):
Diagnostic Markers
,
Therapeutics
,
Therapeutics > Oncology