Search Results - kham+(ryan)+trinh

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Targeted Delivery of IFN-gamma Using Antibody Fusion Proteins (UCLA Case No. 2017-543)

UCLA researchers in the Departments of Microbiology, Immunology & Molecular Genetics (MIMG) and Medicine have developed antibody–cytokine fusion proteins that enable the targeted delivery of active interferon-gamma (IFNγ) for cancer treatment. Interferon-gamma (IFNγ), a type II interferon, is a cytokine released by both natural...

Published: 2/26/2024 | Inventor(s): Sherie Morrison, John Timmerman, Kham (Ryan) Trinh

Keywords(s): Antibody Delivery Platforms, Drug Delivery, Immunotherapy, Life Science Research Tools, Therapeutics & Vaccines

Category(s): Therapeutics, Platforms > Drug Delivery, Platforms > Drug Delivery > Antibody Delivery Platforms, Life Science Research Tools, Therapeutics > Immunology And Immunotherapy

2018-384 ANTIBODY-INTERFERON FUSION PROTEINS FOR ENHANCING ADOPTIVE T CELL THERAPIES FOR THE TREATMENT OF CANCER

UCLA researchers in the Departments of Medicine and Microbiology, Immunology and Molecular Genetics have developed a novel combination therapy for enhanced efficacy of Adoptive T Cell Therapies (ACT): that could enable the adoption of ACT as an effective means to combat multiple cancer subtypes. BACKGROUND:The clinical relevancy of cancer immunotherapy...

Published: 7/19/2023 | Inventor(s): John Timmerman, Patricia Young, Kham (Ryan) Trinh, Sherie Morrison

Keywords(s): Diagnostic Markers & Platforms, Oncology, Therapeutics & Vaccines

Category(s): Diagnostic Markers, Therapeutics, Therapeutics > Oncology

Hybrid IgA/IgG Polymeric Antibodies

Case 1998-610BACKGROUNDIgA is a polymeric effector molecule of the immune system that mainly acts at mucosal surfaces and is highly resistant to extreme pH conditions, whereas IgG is monomeric and acts in the blood at a narrower pH range. IgG is known for its potent complement activation and, in contrast, IgA is unable to fix complement. Combining the...

Published: 7/19/2023 | Inventor(s): Sherie Morrison, Koteswara Chintalacharuvu, Maria Coloma, Kham (Ryan) Trinh, Esther Yoo

Keywords(s): Antibodies, Immunotherapy

Category(s): Life Science Research Tools > Antibodies, Therapeutics > Immunology And Immunotherapy