Search Results - kouki+morizono

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Targeted Lentiviral Transduction of B-Cells With Desired B-Cell Receptor Specificity (UCLA Case No. 2023-237)

UCLA researchers in the Division of Hematology and Oncology in the Department of Medicine, have discovered novel lentiviral vectors that can be used for gene delivery to B-cells and for the development of neutralizing antibodies against viruses. BACKGROUND: Microbial tropism is a microbiology term that describes the types of animals (including human),...

Published: 3/15/2024 | Inventor(s): Kouki Morizono

Keywords(s): B Cell, cell receptor, COVID-19, VIral entry, Virus

Category(s): Therapeutics > Immunology And Immunotherapy

2000-128 TARGETING LENTIVIRAL VECTORS TO SPECIFIC CELLS AND TISSUES

SummaryResearchers in the UCLA Departments of Medicine and Microbiology, Immunology and Molecular Genetics have developed retroviral vectors pseudotyped with a modified Sinbus virus envelope that exhibit reduced tropism and can be used for the targeted transduction of heterologous genes into cells.BackgroundThere have been numerous attempts to develop...

Published: 7/19/2023 | Inventor(s): Irvin S.Y. Chen, Kouki Morizono

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics, Therapeutics > Gene Therapy And Editing