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2014-387 Small Molecule Antagonists of the Pro-Survival Protein MCL-1 (POC 2016)

Small Molecule Antagonists Of The Pro-Survival Protein Mcl-1SUMMARYUCLA Researchers have discovered novel inhibitors to signaling proteins involved in the regulation of apoptosis. MCL-1, which is known to be overexpressed in many cancers, is believed to be upregulated in cancers to prevent the apoptosis pathway.The researchers have developed novel small...

Published: 7/19/2023 | Inventor(s): Patrick Harran, Gordon Shore, James Frederich, Mai Nguyen

Keywords(s): Oncology, Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology (Small Molecules)