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2020-441 OPTICAL IMAGING METHOD FOR INTRAOPERATIVE SURGICAL GUIDANCE AND MARGIN ASSESSMENT BASED ON FLUORESCENCE LIFETIME CONTRAST

UCLA researchers from the Department of Head and Neck Surgery have developed a novel optical imaging method for surgical guidance. BACKGROUND:Biomedical imaging is an indispensable tool to guide in precise tumor removal in comprehensive cancer surgery. Imaging strategies like x-ray, ultrasound, and MRI are principally used to localize large tumors prior...

Published: 7/17/2025 | Inventor(s): Maie St John, Oscar Stafsudd

Keywords(s): Fluorescence, Medical Imaging

Category(s): Medical Devices > Medical Imaging > Fluorescence

2020-493 SELECTIVE SPECTRAL ILLUMINATION METHOD AND SYSTEM FOR OPTICAL IMAGE GUIDED SURGERY

UCLA researchers in the Department of Head and Neck Surgery have developed a novel selective spectral illumination system for optical image-guided surgery. BACKGROUND:In oncological surgery, patient prognosis depends heavily on complete tumor removal. Currently, surgeons have to rely on subjective evaluations (e.g. visual appearance) to distinguish...

Published: 7/17/2025 | Inventor(s): Maie St John, Oscar Stafsudd

Keywords(s): Fluorescence, Medical Imaging

Category(s): Medical Devices > Medical Imaging > Fluorescence

Salivary IL8 and Serum for Oral Cavity and Oropharyngeal Cancer and Probe Immobilization and Signal Amplification for Polymer-Based Biosensor (UCLA Case No. 2013-794)

UCLA researchers in the Department of Dentistry have developed a method of using improved polymer-based biosensors to detect the presence of nucleic acids, proteins, and other analytes in bodily fluids such as saliva in order to diagnose diseases such as oral cancer.BACKGROUND: Highly sensitive and robust detection methodologies, specifically those...

Published: 7/17/2025 | Inventor(s): Maie St John, David Wong, Yang Li, Fang Wei, Wei Liao

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2010-486 SALIVARY IL8 AND SERUM FOR ORAL CAVITY AND OROPHARYNGEAL CANCER AND PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR

Published: 2/14/2025 | Inventor(s): Maie St John, David Wong, Yang Li, Fang Wei, Wei Liao

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2010-392 SALIVARY IL8 AND SERUM FOR ORAL CAVITY AND OROPHARYNGEAL CANCER AND PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR

Published: 2/14/2025 | Inventor(s): Maie St John, David Wong, Yang Li, Fang Wei, Wei Liao

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2008-303 SALIVARY IL8 AND SERUM FOR ORAL CAVITY AND OROPHARYNGEAL CANCER AND PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR

Published: 7/17/2025 | Inventor(s): Maie St John, David Wong, Yang Li, Fang Wei, Wei Liao

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2007-744 SALIVARY IL8 AND SERUM FOR ORAL CAVITY AND OROPHARYNGEAL CANCER AND PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR

Published: 7/17/2025 | Inventor(s): Maie St John, David Wong, Yang Li, Fang Wei, Wei Liao

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2007-527 SALIVARY IL8 AND SERUM FOR ORAL CAVITY AND OROPHARYNGEAL CANCER AND PROBE IMMOBILIZATION AND SIGNAL AMPLIFICATION FOR POLYMER-BASED BIOSENSOR

Published: 7/17/2025 | Inventor(s): Maie St John, Yang Li, Fang Wei, Wei Liao, David Wong

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2003-525 SALIVARY IL8 AND SERUM IL6 FOR ORAL CAVITY AND OROPHARYNGEAL CANCER

Published: 7/17/2025 | Inventor(s): Maie St John, David Wong, Yang Li

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Oncology

Category(s): Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology

2017-537 MULTI-FREQUENCY HARMONIC ARRAY ACOUSTOGRAPHY FOR TARGET IDENTIFICATION (ARRAY IMPLEMENTATION)

SUMMARY:UCLA researchers in the Departments of Head and Neck Surgery, Bioengineering, and Electrical Engineering have developed an imaging modality called vibroacoustography that uses ultra-sound-based technology to identify targets.BACKGROUND: The identification and diagnosis of diseases in target tissue guides surgical intervention. Current surgical...

Published: 2/14/2025 | Inventor(s): Warren Grundfest, Maie St John, Ashkan Maccabi, George Saddik, Zachary Taylor

Keywords(s): Medical Imaging, Other

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