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2019-701 PEPTIDE-BASED INHIBITORS THAT BLOCK AGGREGATION, SEEDING AND CROSS-SEEDING OF AMYLOID BETA AND TAU

UCLA researchers in the Department of Chemistry and Biochemistry have developed novel therapeutics for Alzhiemer’s Disease and other tauoapathies. BACKGROUND:Alzhiemer’s Disease (AD) is a severe neurodegenerative disease characterized by deterioration of the brain cells and loss of multiple cognitive functions. Although AD is the most...

Published: 7/19/2023 | Inventor(s): David Eisenberg, Paul Seidler

Keywords(s): Cns, Therapeutics & Vaccines

Category(s): Therapeutics > CNS and Neurology

2018-348 NOVEL TAU AGGREGATION INHIBITOR PEPTIDE

Novel Tau Aggregation Inhibitor PeptideSUMMARYUCLA researchers from the Department of Chemistry and Biochemistry have developed a novel approach to inhibit the aggregation of tau proteins in the brain, which is linked to over 20 dementias including Alzheimer’s Disease and Chronic Traumatic Encephalopathy.BACKGROUNDAggregation of tau protein is...

Published: 7/19/2023 | Inventor(s): David Eisenberg, Paul Seidler

Keywords(s): Cns, Gene Editing Systems, Gene Therapy, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Gene Therapy And Editing