Search Results - steven+dubinett

4 Results

Sort By:

Combination Cancer Therapy Methods and Agents (UCLA Case No. 2024-084)

UCLA researchers from the Department of Medicine, Pathology, & Laboratory Medicine and Molecular & Medical Pharmacology have identified a novel cell-based therapy that leads to enhanced immunotherapy efficacy and overcomes treatment resistance to immune checkpoint blockade in non-small cell lung cancer. BACKGROUND: Non-small cell lung cancer...

Published: 11/4/2024 | Inventor(s): Bin Liu, Steven Dubinett

Keywords(s): anti-tumor immunity, cell-based therapy, Immune checkpoint blockade, Immunotherapy, non-small cell lung cancer, treatment resistance, Tumor microenvironment, Vaccines

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Respiratory And Pulmonary

2019-044: Sodium-Dependent Glucose Transporter 2 as a Diagnostic and Therapeutic Target for Early-Stage Cancer

SUMMARY: UCLA researchers in the Department of Medicine have developed a clinical screening method for early-stage lung cancer utilizing a newly discovered biomarker and subsequently shown that inhibitors of this biomarker result in cancer interception. BACKGROUND: The National Cancer Institute reports that lung cancer accounts for 28% of all...

Published: 9/5/2023 | Inventor(s): Claudio Scafoglio, Steven Dubinett

Keywords(s):

Category(s): Diagnostic Markers > Targets And Assays, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary

Gene Modified Autologous Dendritic Cells in Combination with Anti-PD1 Therapy for Metastatic Lung Cancer (UCLA Case No. 2019-844)

UCLA researchers at David Geffen School of Medicine have developed a novel approach of in situ vaccination by intratumorally injecting chemokine gene-modified dendritic cells to sensitize non-responsive non-small cell lung cancer (NSCLC) to anti-PD-1/PD-L1 immunotherapy. BACKGROUND:The treatment of non-small cell lung cancer (NSCLC) has...

Published: 4/9/2024 | Inventor(s): Steven Dubinett

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Immunotherapy, Medical Devices and Materials, Oncology, Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Therapeutics > Gene Therapy And Editing, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy

Combination Immunotherapy (UCLA Case No. 2015-348)

Combination ImmunotherapySUMMARYUCLA researchers have developed a combination immunotherapy for lung cancer that functions by evoking anti-tumor immune responses in lung cancer patients.BACKGROUNDLung cancer is a challenging health problem, claiming more than 1.1 million deaths worldwide annually. Despite incredible medical progress, the long-term survival...

Published: 2/14/2024 | Inventor(s): Jay Lee, Steven Dubinett, Sherven Sharma

Keywords(s): Immunotherapy, Oncology Immunotherapy, Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy