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Hybrid IgA/IgG Polymeric Antibodies
Case 1998-610BACKGROUNDIgA is a polymeric effector molecule of the immune system that mainly acts at mucosal surfaces and is highly resistant to extreme pH conditions, whereas IgG is monomeric and acts in the blood at a narrower pH range. IgG is known for its potent complement activation and, in contrast, IgA is unable to fix complement. Combining the...
Published: 7/19/2023   |   Inventor(s): Sherie Morrison, Koteswara Chintalacharuvu, Maria Coloma, Kham (Ryan) Trinh, Esther Yoo
Keywords(s): Antibodies, Immunotherapy
Category(s): Life Science Research Tools > Antibodies, Therapeutics > Immunology And Immunotherapy