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Small Molecules that Inhibit RNA Binding Protein IGF2BP3 in Cancer (UCLA Case No. 2023-215)
UCLA researchers in the Department of Pathology and Laboratory Medicine have developed small molecules which inhibits the protein IGF2BP3, a highly expressed oncofetal protein in certain cancers, especially in B-acute lymphoblastic leukemia. BACKGROUND: Cancer remains the second leading cause of death in the U.S. Advancements in targeted therapies...
Published: 11/15/2024
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Inventor(s):
Dinesh Rao
Keywords(s):
blood cancers
,
Cancer
,
cancer inhibition
,
leukemia
Category(s):
Therapeutics > Oncology
2013-475 Diagnostic, Prognostic, and Therapeutic Uses of Non-Coding RNAs in Leukemia
Diagnostic, Prognostic and Therapeutic Uses of Non-Coding RNAs in LeukemiaSUMMARYThe Rao group at UCLA has developed a method of using lincRNA expression levels as a diagnostic and prognostic tool for B acute lymphoblastic leukemia. Furthermore, regulation of certain leukemia-associated lincRNA may hold therapeutic potential.BACKGROUNDAcute lymphoblastic...
Published: 7/19/2023
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Inventor(s):
Dinesh Rao
,
Ella Waters
,
Norma Rodriguez-Malave
,
Thilini Fernando
Keywords(s):
Category(s):
Life Science Research Tools
,
Diagnostic Markers > Targets And Assays
,
Therapeutics
,
Therapeutics > Oncology > Oncology (Small Molecules)