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Quantitative Myositis Lung Disease Score (QMS): Machine Learning Techniques for Quantitative CT Scoring in Myositis Lung Disease (Case No. 2026-189)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a quantitative imaging tool designed to standardize the diagnostic scoring of myositis lung disease (MLD) for improved patient intervention and monitoring. Background: Myositis lung disease (MLD) is a complex autoimmune condition characterized by muscle inflammation...

Published: 6/4/2026 | Inventor(s): Matthew Brown, Sangmee Bae, Grace Hyun Kim, Jonathan Goldin

Keywords(s):

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > CT, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools, Electrical, Electrical > Signal Processing, Electrical > Instrumentation, Electrical > Imaging

Gene Editing of Monogenic Disorders in Human Hematopoietic Stem Cells

Case 2018-372Researchers at the UCLA Department of Microbiology, Immunology & Molecular Genetics have developed novel methods to achieve efficient, precise gene integration and effective expression of cDNA cassettes to express normal versions of genes in hematopoietic stem cells.BACKGROUNDHematopoietic stem cells (HSCs) have great therapeutic potential...

Published: 6/3/2026 | Inventor(s): Donald Kohn, Caroline Kuo, Zulema Romero Garcia, Roger Hollis

Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Life Science Research Tools

Category(s): Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Life Science Research Tools

Device and Method for Recording-Guided Neuromodulation via the Olfactory Cleft (Case No. 2026-077)

Summary: UCLA researchers in the Department of Neurology have developed a minimally invasive, recording-guided closed-loop neuromodulation device enabling transnasal access to olfactory-cleft pathways for targeted modulation of deep limbic brain circuits. Background: The olfactory bulb provides direct anatomical and functional pathways to the limbic...

Published: 6/3/2026 | Inventor(s): Kevin Bickart, Mahmoud Omidbeigi

Keywords(s): Brain, Deep Brain Stimulation, Deep Brain Stimulation Current Mirror Output Impedance, device stability, Electrical Brain Stimulation, Electrical stimulation, minimally invasive device, neural stimulation, Neuromodulation, Neurostimulation, noninvasive, non-invasive, non-invasive monitoring, Transcutaneous Electrical Nerve Stimulation

Category(s): Software & Algorithms > Bioinformatics, Therapeutics > CNS and Neurology, Software & Algorithms > Digital Health, Electrical, Life Science Research Tools, Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Neural Stimulation

A Device for the Direct Measurement of Solar-Induced Chlorophyll Fluorescence in the Far-Red Spectral Range (SIF-SBR) (Case No. 2024-183)

Summary: UCLA researchers in the Department of Atmospheric and Oceanic Sciences have developed a novel and compact device for direct, real-time measurement of solar-induced chlorophyll fluorescence, enabling accurate monitoring of plant photosynthetic activity without complex calibration or spectral retrieval procedures. Background: Accurate monitoring...

Published: 5/8/2026 | Inventor(s): Jochen Stutz, Jonas Kuhn

Keywords(s): Agricultural & plant biology research, Agriculture, Chemical, concentrated solar radiation, Ecosystem monitoring, Fluorescence, low-power architecture, low-power device, low-power sensor, operating range, Photon, photosynthetic activity, photosynthetic monitoring, Plant fluorescence, Plant proximal remote sensing, Precision Agriculture, Proximal remote sensing, real-time, real-time sensing/monitoring/tracking, Signal Processing, Signal-To-Noise Ratio, Solar Energy, spectral density

Category(s): Energy & Environment, Energy & Environment > Energy Efficiency, Energy & Environment > Carbon Capture, Energy & Environment > Water Monitoring & Treatment, Life Science Research Tools, Life Science Research Tools > Research Methods, Optics & Photonics, Optics & Photonics > Remote Sensing, Optics & Photonics > Spectroscopy, Life Science Research Tools > Field Equipment

Active Electromagnetic Interference Suppression for Magnetic Resonance Imaging-Guided Interventions (Case No. 2026-217)

Summary: UCLA researchers in the Department of Radiological Sciences have developed a software-based active electromagnetic interference suppression solution for real-time MRI-guided interventions. Background: Microwave ablation (MWA) has emerged as the preferred thermal ablation modality for treating non-surgical patients with primary and metastatic...

Published: 4/16/2026 | Inventor(s): Holden Wu, Qing Dai

Keywords(s):

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing, Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Lab Equipment, Medical Devices > Monitoring And Recording Systems, Therapeutics, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Mechanical, Mechanical > Instrumentation, Mechanical > Sensors, Electrical, Electrical > Electronics & Semiconductors, Electrical > Signal Processing, Electrical > Instrumentation, Electrical > Imaging

Highly Miniaturized Closed-Loop Biosensing and Drug Delivery (Case No. 2025-276)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an implantable closed-loop system that integrates electrochemical biosensing, wireless signal transmission, and programmable drug release. Background: Conventional disease management systems rely on single-point measurements and discrete interval drug...

Published: 2/5/2026 | Inventor(s): Aydin Babakhani, Iman Habibagahi, Hamid Jafarisharemi, Roshan Mathews

Keywords(s): biomedical implantation, biomedical sensors, Drug Delivery, Drug monitoring, Implant (Medicine), implantable sensors, Medical Device, minimally invasive drug delivery systems, on-demand drug delivery, personalized dose assessment, Smart medical device, Therapeutics, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health, Wireless, wireless communication

Category(s): Life Science Research Tools, Electrical, Medical Devices, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms

Lesion Estimation with Geometric Object Measurement (LE-GEOM) (Case No. 2025-077)

Summary: UCLA researchers in the Department of Radiology have developed a novel, automated approach for tumor assessment by determining RANO-compliant tumor diameters from tumor segmentation data. Background: MRI tumor measurements are critical in both clinical trials and clinical practice. Traditionally, radiologists manually assessed tumors by...

Published: 2/26/2026 | Inventor(s): Benjamin Ellingson, Francesco Sanvito, Catalina Raymond

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Medical Devices, Medical Devices > Medical Imaging, Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Bioinformatics

An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)

Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...

Published: 1/13/2026 | Inventor(s): Pei-Yu Chiou, Xiang Zhang

Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping

Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies

Mental Health Functional Movement Scale (MH-FMS) (Case No. 2025-021)

Summary: UCLA researchers in the Department of Psychiatry and Behavioral Sciences have created a novel assessment platform that objectively measures how the brain, body, and autonomic nervous system respond to stress and regulate emotion during real-time movement. By integrating a shear-stress–based neurovascular framework with a polyvagal-informed...

Published: 12/17/2025 | Inventor(s): Naser Ahmadi, Mike Ramirez, Julien Pineau

Keywords(s): blood flow management, Cardiovascular, cellular, clinical care methodology, clinical decision support, Clinical decision support system, clinical mental health, Clinical tool, exercise physiology, Hemodynamics, Mental health, neurobehavioral impairment, Neurocognitive, Neurocognitive Scientific Method, neurodevelopment, neurological disorders, Neuropsychological Test, neuroscience, Neurostimulation, Psychiatry / Mental Health

Category(s): Diagnostic Markers, Life Science Research Tools, Medical Devices, Medical Devices > Hospital Systems, Therapeutics, Therapeutics > Psychiatry And Mental Health

Machine Learning to Predict Physiological Age Using Features Extracted From Arterial Blood Pressure (ABP) Waveforms (Case No. 2025-264)

Summary: UCLA researchers in the Department of Anesthesiology have introduced a novel machine learning model that accurately predicts physiological aging by analyzing features extracted from patients’ arterial blood pressure (ABP) waveforms. This approach enables efficient, data-driven assessment of biological aging in clinical settings to facilitate...

Published: 12/5/2025 | Inventor(s): Maxime Cannesson, Ravi Pal

Keywords(s): Aging, Anesthesiology, biomedical sensors, clinical care methodology, clinical decision support, clinical outcome, Clinical tool, Computer-Aided Diagnosis, consumer health products, Digital Health, digital health system, Fatigue (Medical) , Health and fitness, health risk assessment, Machine Learning, machine learning modeling, Medical Device, Medical diagnostics, Monitoring (Medicine), personalized medicine, Preventive Medicine, public health monitoring, Smart medical device, Structural health monitoring, Telemedicine

Category(s): Diagnostic Markers, Diagnostic Markers > Aging, Life Science Research Tools, Medical Devices

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