Search Results - life+science+research+tools

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Broad-Band Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Neuropsychiatric Disorders (Case No. 2025-99J)

Summary: Researchers in UCLA's Semel Institute and Department of Psychiatry have developed an innovative approach to treating depression by optimizing repetitive Transcranial Magnetic Stimulation (rTMS), improving its effectiveness for the treatment of Major Depressive Disorder (MDD) and possibly diseases of the mind and brain. Background: Depression...

Published: 10/9/2025 | Inventor(s): Andrew Leuchter, Juliana Corlier, Thomas Valles

Keywords(s): Bioelectromagnetics, Brain, Deep Brain Stimulation, Electrical Brain Stimulation, energy-efficient, frequency modulation, Magnetic Field, Medical Device, medication efficacy, neural information, neural network, neural networks, neural signals, neural stimulation, neurobehavioral impairment, Neurocognitive, neurological disorders, Neuromodulation, Neuron, neurons, neuroscience, Neurostimulation, pulsed load modulation, therapy, treatment efficacy

Category(s): Medical Devices, Medical Devices > Neural Stimulation, Life Science Research Tools, Therapeutics > CNS and Neurology, Therapeutics

Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)

Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...

Published: 10/1/2025 | Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun

Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery

High-Throughput Cell Screening With Interferometric Cytometry (Case No. 2007-720)

Summary The combined technology platform encompasses optical cytometry via interferometric membrane probing and cell mechanical / membrane property characterization, using reflective microparticles and interferometric imaging to measure deformation and viscoelastic response of live cells. The approach links physical membrane dynamics to cellular state,...

Published: 9/25/2025 | Inventor(s): Michael Teitell, James Gimzewski, Jason Reed

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems

Pulsed Laser Triggered High Speed Microfluidic Switch and Applications in Flourescent Activated Cell Sorting (Case No. 2009-063)

Summary UCLA researchers have developed a pulsed-laser triggered microfluidic switching mechanism capable of sub-100 µs switching (e.g. ~70 µs), enabling ultrafast cell/particle sorting in a microfluidic fluorescence-activated cell sorting (µFACS) platform using cavitation bubbles rather than mechanical valves. Background Flow cytometry...

Published: 9/25/2025 | Inventor(s): Pei-Yu Chiou, Ting Hsiang Wu

Keywords(s):

Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods

TRP: Generation of Therapeutic Human Anti-TROP2 Extracellular Domain Antibodies (UCLA Case No. 2015-958)

Tangible Research Property (TRP) Contact UCLA Technology Development Group to learn more.

Published: 9/24/2025 | Inventor(s): Owen Witte

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies

TRP: Precursor Towards 18F-Clofarabine (UCLA Case No. 2017-379)

Tangible Research Property (TRP) Contact UCLA Technology Development Group to learn more.

Published: 9/29/2025 | Inventor(s): Caius Radu

Keywords(s):

Category(s): Life Science Research Tools

Continuous Whole-Chip 3-Dimensional Dep Cell Sorter and Its Fabrication (Case No. 2012-612)

Summary Researchers at UCLA have developed a continuous, whole-chip, three-dimensional dielectrophoretic (DEP) cell sorting device, integrating multi-layer microfluidics and electrode geometries to sort cells or particles throughout the thickness of a microfluidic chip, not merely at a single plane. Background Microfluidic cell sorting is vital in...

Published: 9/24/2025 | Inventor(s): Pei-Yu Chiou, Yu Jui Fan, Yu Chun Kung, Kuo Wei Huang

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Optics & Photonics, Optics & Photonics > Microscopy, Electrical, Electrical > Imaging

Pulse Laser Driven High Speed, On-Demand, and Multiplexed Droplet Generator (Case No. 2013-184)

Summary UCLA researchers have developed a high-speed, on-demand microfluidic droplet platform that allows rapid and precise generation, manipulation, and merging of microdroplets for advanced lab-on-a-chip applications. The technology enables controlled droplet initiation and synchronized merging at high throughput, making it a versatile platform for...

Published: 9/24/2025 | Inventor(s): Pei-Yu Chiou, Michael Teitell, Ting Hsiang Wu, Yue Chen, Yu Chun Kung

Keywords(s):

Category(s): Optics & Photonics, Optics & Photonics > Lasers, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Research Methods, Life Science Research Tools > Cell Counting And Imaging

TRP: Helper-Dependent Adenoviral Vector Expressing Murine Carbamoyl Phosphate Synthetase 1 (UCLA Case No. 2018-907)

Tangible Research Property (TRP) Contact UCLA Technology Development Group to learn more.

Published: 9/23/2025 | Inventor(s): Gerald Lipshutz

Keywords(s):

Category(s): Life Science Research Tools

TRP: Prostate Stem Cell Antigen (PSCA) Antibody Material (Related to UCLA Case Nos. 2004-190, 2006-490, 2008-088, 2019-335)

Tangible Research Property (TRP) Contact UCLA Technology Development Group to learn more.

Published: 9/23/2025 | Inventor(s): Anna Work

Keywords(s):

Category(s): Life Science Research Tools

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