Search Results - life+science+research+tools+%3e+mass+spectrometry

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Silyl Ether Enables Chemoproteomic Interaction and Target Engagement (SEE-CITE) (UCLA Case No. 2024-194)

UCLA researchers from the Department of Biological Chemistry have developed a chemoproteomic platform for high-coverage, site-specific mapping of small-molecule–protein interactions using a cleavable silyl ether–based photoaffinity probe design. BACKGROUND: Small molecule drugs rely on specific and selective interactions with protein targets...

Published: 11/4/2025 | Inventor(s): Keriann Backus

Keywords(s):

Category(s): Life Science Research Tools > Mass Spectrometry, Life Science Research Tools > Research Methods, Therapeutics > Oncology

Methods for Determining Drug-Target Structures by Combining Mass Spectrometry and Electron Diffraction (UCLA Case No. 2025-229)

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel approach to study protein-ligand interactions by integrating native mass spectrometry with electron diffraction. BACKGROUND: The accurate characterization of small molecule-protein interactions is crucial for biomedical research. High-throughput structural methods,...

Published: 10/29/2025 | Inventor(s): Jose Rodriguez

Keywords(s):

Category(s): Life Science Research Tools, Life Science Research Tools > Mass Spectrometry, Chemical > Synthesis, Chemical > Chemical Sensors, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers > Targets And Assays, Electrical > Sensors, Electrical > Instrumentation, Life Science Research Tools > Research Methods, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Screening Libraries, Life Science Research Tools > Lab Equipment, Mechanical > Sensors, Mechanical > Instrumentation, Optics & Photonics > Microscopy, Optics & Photonics > Spectroscopy

Virtual Impactor-Based Label-Free Bio-Aerosol Detection Using Holography and Deep Learning (Case No. 2023-037)

Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a virtual aerosol detection method that combines imaging and deep learning to sense and classify bio-aerosols without any external labeling or post processing steps. Background: Bio-aerosol detection and classification is pivotal to understanding and...

Published: 2/14/2025 | Inventor(s): Aydogan Ozcan, Yi Luo, Tairan Liu

Keywords(s): air quality measurement, Artificial Neural Network, bioterrorism, computational imaging, Deep learning-based sensing, Digital Electronics, Digital Holography, Digital Signal Processing, Imaging, label-free imaging, label-free sensing, Mass Spec, pollen detection, Sensors, virtual impactors

Category(s): Electrical, Electrical > Sensors, Electrical > Imaging, Life Science Research Tools, Life Science Research Tools > Mass Spectrometry

2012-282 Mechanical Phenotyping Of Single Cells: High Throughput Quantitative Detection And Sorting

SUMMARYUCLA researchers in the Department of Integrative Biology & Physiology and Bioengineering have developed a novel high throughput mechanically activated sorting device. BACKGROUNDCells are soft, viscoelastic materials whose main structural components are proteins and membranes and whose mechanical phenotype can be significantly altered during...

Published: 7/17/2025 | Inventor(s): Amy Rowat, David Hoelzle, Clara Chan

Keywords(s):

Category(s): Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Mass Spectrometry