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Biomaterial-Based Vaccine Booster to Enhance Long-Term Immunity (UCLA Case No. 2021-170)
UCLA researchers have developed injectable, cell-free, and biomaterial-based microparticles that can engage with tissue resident immune cells and enhance long-term immunity. It is the first biomaterial-based, targeted approach to induce T memory stem cells (TMSCs) in vivo. The approach was demonstrated for
SARS-CoV-2
but can be used for any vaccine....
Published: 2/26/2024
|
Inventor(s):
Mohammad Hasani-Sadrabadi
,
Song Li
,
Manish Butte
Keywords(s):
aAPCs
,
Aging
,
artificial presenting cells
,
cytokines
,
elderly
,
immunosenescence
,
microparticles
,
platform technology
,
SARS-CoV-2
,
T memory stem cells
,
TMSCs
,
Vaccines
Category(s):
Therapeutics > Infectious Diseases
,
Therapeutics > Oncology
Nrf2 Agonist as Therapeutic Modality to Increase Antiviral Efficacy of Existing Antivirals Against Coronavirus Infections (UCLA Case No. 2022-325)
UCLA researchers in the School of Medicine’s department of Infectious Disease have identified a novel therapeutic approach that can supplement existing FDA approved treatments for SARS-CoV2-2 infections to provide robust treatments against morbidity. BACKGROUND: The World Health Organization reports that as of June 2023, there have been over...
Published: 2/23/2024
|
Inventor(s):
Theodoros Kelesidis
Keywords(s):
Coronavirus
,
COVID-19
,
Paxlovid
,
SARS-CoV-2
,
Viral Medication
Category(s):
Therapeutics > Infectious Diseases