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Generation of Therapeutic Human Anti-Trop-2 Extracellular Domain Antibodies (UCLA Case No. 2026-026)
UCLA researchers from the Department of Molecular and Medical Pharmacology and the Department of Microbiology, Immunology and Molecular Genetics have developed a panel of human antibodies and chimeric antigen receptors targeting Trop-2, providing diagnostic and therapeutic resources for targeting Trop2-driven cancer. BACKGROUND: Trophoblast cell surface...
Published: 12/23/2025
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Inventor(s):
Tanya Stoyanova
,
Owen Witte
Keywords(s):
Category(s):
Diagnostic Markers > Cancer
,
Diagnostic Markers > Targets And Assays
,
Life Science Research Tools > Antibodies
,
Therapeutics > Oncology
,
Therapeutics > Immunology And Immunotherapy
Lipid Nanoparticle-Mediated Delivery of Gene Editing Reagents for Targeted Disruption of Oncogenic Drivers in C-Myc Overexpressing Malignancies (UCLA Case No. 2025-9A9)
Contact UCLA Technology Development Group to learn more.
Published: 9/19/2025
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Inventor(s):
Steven Jonas
,
Tanya Stoyanova
Keywords(s):
Category(s):
Therapeutics > Gene Therapy And Editing
,
Therapeutics > Oncology