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2021-259 CLOUDEAD: EVEN AEROSOL DISTRIBUTION
SUMMARY: UCLA Researchers in the Departments of Bioengineering and Pediatrics have developed a tool for efficient toxicology tests of electronic cigarette products. BACKGROUND: The use of electronic cigarettes (e-cigarettes) has been increasing since 2011, especially amongst American youths. Pediatricians and other healthcare providers are increasingly...
Published: 9/5/2023
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Inventor(s):
Steven Jonas
,
Brigitte Gomperts
,
Jae Park
,
Kayla Choi
,
Rini Desai
,
Parsa Iranmahboub
,
Samantha Rafeedie
,
Gail Vinnacombe-Willson
,
Ahanti Bommireddipalli
,
Valentine Zinchenko
Keywords(s):
Category(s):
Life Science Research Tools > Lab Equipment
,
Life Science Research Tools
Silicon Nanovolcanos for Gene Delivery with High Efficiency and Cell Viability
INTRO SENTENCE: UCLA researchers in the department of Chemistry and Biochemistry have developed a novel technique of intracellular cargo delivery using nanovolcanos with high efficiency and cell viability.BACKGROUND: Intracellular cargo delivery facilitates cellular reprogramming and development of next generation gene and cellular therapies....
Published: 7/19/2023
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Inventor(s):
Paul Weiss
,
Hsian-Rong Tseng
,
Qing Yang
,
Xiaobin Xu
,
Shuang Hou
,
Steven Jonas
Keywords(s):
Chemical Manufacturing & Industrial/Bulk Chemicals
,
Drug Delivery
,
Gene Therapy
,
Other Polymers
Category(s):
Platforms > Drug Delivery
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Platforms > Drug Delivery > Other Polymers
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Chemical > Industrial & Bulk Chemicals
,
Therapeutics > Gene Therapy And Editing
2017-109 High-Throughput Microfluidic Gene-Editing Via Cell Deformability within Microchannels
High-Throughput Microfluidic Gene-Editing via Cell Deformability within MicrochannelsSUMMARYUCLA researchers in the Departments of Pediatrics and Chemistry & Biochemistry have developed a microfluidic device for delivery of biomolecules into living cells using mechanical deformation, without the fouling issues in current systems.BACKGROUNDGene therapy...
Published: 7/19/2023
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Inventor(s):
Steven Jonas
,
Paul Weiss
,
Ali Khademhosseini
,
Joanna Aizenberg
,
Xu Hou
Keywords(s):
Drug Delivery
,
Gene Editing Systems
,
Gene Therapy
,
Genetic Disease
,
Life Science Research Tools
,
Microfluidics And Mem's
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Microfluidics And Mems
,
Platforms > Drug Delivery
,
Therapeutics
,
Therapeutics > Gene Therapy And Editing
2017-454 High Throughput Intracellular Delivery of Biomolecular Cargos via Vibrational Cell Deformability within Microchannels
High-Throughput Intracellular Delivery of Biomolecular Cargos via Vibrational Cell Deformability within MicrochannelsSUMMARYUCLA Researchers in the Departments of Chemistry and Materials Science & Engineering have developed a novel means of delivering intracellular cargo.BACKGROUNDGene editing of various cell types remains the focus of many therapeutic...
Published: 7/19/2023
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Inventor(s):
Paul Weiss
,
Dan Wilkinson
,
Adam Stieg
,
Steven Jonas
Keywords(s):
Drug Delivery
,
Gene Editing Systems
,
Gene Therapy
,
Life Science Research Tools
,
Microfluidics And Mem's
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Microfluidics And Mems
,
Platforms > Drug Delivery
,
Therapeutics > Gene Therapy And Editing
2018-437 SCALABLE LIPID BILAYER MICROFLUIDICS FOR HIGH-THROUGHPUT GENE EDITING
Scalable Lipid Bilayer Microfluidics for High-Throughput Gene EditingSUMMARYResearchers led by Paul Weiss from the Department of Chemistry and Pediatrics at UCLA have created a new microfluidic device for high-throughput gene editing of cells.BACKGROUNDGene editing has many potential applications, allowing for the modification of immune cells to target...
Published: 7/19/2023
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Inventor(s):
Jason Belling
,
Paul Weiss
,
Steven Jonas
,
Joshua Jackman
,
Nam-Joon Cho
Keywords(s):
Drug Delivery
,
Gene Editing Systems
,
Gene Therapy
,
General Device Coatings
,
Life Science Research Tools
,
Medical Devices and Materials
,
Microfluidics And Mem's
,
Nucleic Acids
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Microfluidics And Mems
,
Medical Devices
,
Medical Devices > Coatings
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Platforms > Drug Delivery
,
Therapeutics
,
Therapeutics > Gene Therapy And Editing
,
Platforms > Drug Delivery > Nucleic Acids
2018-446 MULTIPLE-PATTERNING NANOSPHERE LITHOGRAPHY
Multiple-Patterning Nanosphere LithographySUMMARYResearchers led by Paul Weiss from the Department of Chemistry and Biochemistry at UCLA have developed a novel technique that solves the scalability issue in the fabrication of three-dimensional nanostructures.BACKGROUNDConfigurable three-dimensional nanostructures have a wide range of applications spanning...
Published: 7/19/2023
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Inventor(s):
Xiaobin Xu
,
Qing Yang
,
Natcha Wattanatorn
,
Chuanzhen Zhao
,
Logan Stewart
,
Steven Jonas
,
Paul Weiss
Keywords(s):
Photonics
Category(s):
Optics & Photonics
2018-436 GUIDED MAGNETIC NANOSPEARS FOR TARGETED AND HIGH-THROUGHPUT INTRACELLULAR DELIVERY
Guided Magnetic Nanospears For Targeted And High-Throughput Intracellular DeliverySUMMARYUCLA researchers in the Department of Chemistry & Biochemistry and Department of Molecular & Medical Pharmacology have developed novel magnetic nanostructures that can be used to carry and/or deliver biomolecular cargo intracellularly to cells.BACKGROUNDCurrent...
Published: 7/19/2023
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Inventor(s):
Steven Jonas
,
Hsian-Rong Tseng
,
Shuang Hou
,
Paul Weiss
Keywords(s):
Drug Delivery
,
Life Science Research Tools
,
Nanoparticles
,
Other Reagents
Category(s):
Life Science Research Tools
,
Life Science Research Tools > Other Reagents
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Platforms > Drug Delivery
,
Platforms > Drug Delivery > Nanoparticles