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Method of Creating Hydrogels Through Oxime Bond Formation (UCLA Case No. 2013-180)

UCLA researchers led by Professor Heather Maynard in the Department of Chemistry have developed a method for creating hydrogels using a patented and specific type of chemical reaction called oxime bond formation (or oxime ligation). BACKGROUND: While many methods exist to create hydrogels (cross-linked materials used in biomedicine), most suffer from...

Published: 10/2/2025 | Inventor(s): Heather Maynard, Tatiana Segura, Gregory Grover, Jonathan Lam

Keywords(s):

Category(s): Platforms > Drug Delivery, Therapeutics > Oncology, Chemical > Polymers

2020-167: Hydrogel Filler Prevents Cerebral Atrophy

UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel treatment to prevent cerebral atrophy after stroke through the injection of a gel into the stroke core. BACKGROUND:Stroke is the leading cause of adult long-term disability and affects 795,000 Americans every year. Immediately following stroke onset, the...

Published: 2/14/2025 | Inventor(s): Tatiana Segura

Keywords(s): Cns, Medical Devices and Materials, Therapeutics & Vaccines

Category(s): Therapeutics > CNS and Neurology

2016-788 HYDROGEL FOR ENGINEERED IMMUNE RESPONSE TO D-CHIRALITY PEPTIDES

Case No. 2016-788SUMMARYUCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel biomaterial that can be used as a therapeutic for cancer, wound healing and other diseases.BACKGROUNDImmunotherapy, the modulation of immune response to drive tissue-specific expression has tremendous potential as a therapeutic...

Published: 7/17/2025 | Inventor(s): Tatiana Segura, Donald Griffin, Philip Scumpia

Keywords(s): Therapeutics & Vaccines

Category(s): Therapeutics