Search Results - heather+maynard

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2015-798 NONCRUSHABLE PILL FORMULATIONS

SUMMARY: UCLA Researchers in the Department of Chemistry have developed a drug formulation for opioids capable of deterring drug abuse. BACKGROUND: It is estimated that more than 115 Americans a day, died to opioid overdose in 2016. The currently projected estimate is that this number will increase to over 150 Americans a day fatally overdosing on opioids....

Published: 7/19/2023 | Inventor(s): Heather Maynard, Erhan Bat

Keywords(s): Drug Delivery, Nanoparticles, Other Polymers

Category(s): Platforms > Drug Delivery > Other Polymers, Platforms > Drug Delivery > Nanoparticles

2014-554 TREHALOSE HYDROGELS FOR STABILIZATION AND DELIVERY OF PROTEINS

Trehalose Hydrogels For Stabilization And Delivery Of ProteinsCase No. 2014-554-0SUMMARYUCLA researchers in the Department of Chemistry and Biochemistry have developed a novel trehalose hydrogel to help stabilize proteins for drug delivery.BACKGROUNDProteins are at the core of biologic drugs and are used to treat a range of disease states including...

Published: 7/19/2023 | Inventor(s): Heather Maynard

Keywords(s): Drug Delivery, Medical Devices and Materials, Other Polymers, Therapeutics & Vaccines

Category(s): Medical Devices, Platforms > Drug Delivery, Therapeutics, Platforms > Drug Delivery > Other Polymers

2012-340 A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic Application

A Novel Basic Fibroblast Growth Factor Conjugate for Broad Therapeutic ApplicationSUMMARYUCLA scientists have developed a novel polymer conjugate of basic fibroblast growth factor (bFGF) for use in commercial and possibly clinical applications. This is the first bFGF conjugate to enhance bioactivity and stability under environmental stressors. BACKGROUNDBasic...

Published: 7/19/2023 | Inventor(s): Heather Maynard, Thi Nguyen

Keywords(s): Catalysts, Dermatology, Other Polymers, Therapeutics & Vaccines

Category(s): Chemical > Synthesis, Therapeutics, Therapeutics > Dermatology, Platforms > Drug Delivery > Other Polymers

2012-422 PolyProtek: Platform for Delivering and Stabilizing Therapeutic Biologics, Vaccines, and Industrial Enzymes

PolyProtek: Platform for Delivering and Stabilizing Therapeutic Biologics, Vaccines, and Industrial EnzymesSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have designed an improved version of trehalose-based glycopolymer as a degradable alternative to PEG for the purpose of stabilizing a protein during storage and transport.BACKGROUNDA...

Published: 7/19/2023 | Inventor(s): Heather Maynard, Juneyoung Lee, Rock Mancini

Keywords(s):

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base

2017-459 Noncrushable Pill Formulations

Noncrushable/Nonabusable Pill FormulationsSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have developed novel abuse-deterrent opioid formulations from elastomers that resist crushing at room temperature and upon heating or cooling. The formulation also contains a dual-enzyme responsive system whereby sequential digestion by...

Published: 7/19/2023 | Inventor(s): Heather Maynard, Samantha Paluck, Natalie Boehnke

Keywords(s): Drug Delivery, Peptide Base, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base, Therapeutics

2017-446 Dual-Enzyme Responsive Peptides

Dual-Enzyme Responsive PeptidesSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry have developed a dual-enzyme responsive peptide system that requires sequential digestion by two separate enzymes for cleavage at the C-terminal position of lysine.BACKGROUNDDue to their high selectivity and specificity, enzyme responsive systems...

Published: 7/19/2023 | Inventor(s): Heather Maynard, Natalie Boehnke

Keywords(s): Drug Delivery, Peptide Base

Category(s): Platforms > Drug Delivery, Platforms > Drug Delivery > Peptide Base