Search Results - todd+yeates

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2020-922 A Universal Designed Protein Cage for Sensing and Responding to Any Other Protein Molecule

SUMMARY: UCLA researchers in the Department of Chemistry and Biochemistry have designed and developed a protein cage which can be easily tailored to sense other proteins, opening in response, and thus delivering enclosed biological compounds across a wide variety of applications, including biosensing, molecular diagnostics, and targeted drug delivery....

Published: 9/5/2023 | Inventor(s): Todd Yeates

Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Diagnostic Test, Drug Delivery

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Platforms > Drug Delivery, Platforms > Drug Delivery > Nucleic Acid Platform Systems, Platforms > Drug Delivery > Nanoparticles, Platforms > Drug Delivery > Nucleic Acids

2015-811 MI-181: A Potent Small Synthetic Microtubule-Targeting AntiCancer Agent

MI-181: A Potent Small Synthetic Microtubule-Targeting Anticancer AgentSUMMARYUCLA researchers in the Department of Chemistry & Biochemistry and Department of Molecular & Medical Pharmacology have discovered compound MI-181 and successfully synthesized its derivatives and analogs, which have the potential for use in cancer therapy by arresting...

Published: 7/19/2023 | Inventor(s): Robert Damoiseaux, Jorge Torres, Todd Yeates, Dan Mcnamara, Silvia Senese

Keywords(s): Oncology, Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines

Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology (Small Molecules)

A Method to Design Self-Assembling Proteins

Case 1999-246BACKGROUNDUnderstanding the roles that molecular structure and self-assembly play in determining molecular architecture helps provide researchers with the possibility of designing unique materials using nanotechnology. Molecular self-assembly entails designing various molecules so shape-complementarity causes them to aggregate into specified...

Published: 7/19/2023 | Inventor(s): Todd Yeates, Christos Colovos, Jennifer Padilla

Keywords(s): Drug Delivery, Therapeutics & Vaccines

Category(s): Platforms > Drug Delivery, Therapeutics