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mTORC2 Specific Inhibitors
Case 2017-517UCLA researchers have identified and characterized mTORC2-specific inhibitors useful as a novel treatment of glioblastoma.BACKGROUNDGlioblastoma (GBM) is a highly malignant and invasive primary brain tumor that is difficult to treat with total surgical resection or chemotherapy. Two-year survival rate of GBM is only 30%, and patients that...
Published: 7/19/2023   |   Inventor(s): Michael Jung, Joseph Gera, Alan Lichtenstein, Angelica Benavides-Serrato, Brent Holmes, Jihye Lee
Keywords(s): Oncology, Oncology (Small Molecules, Peptides and Antibodies), Therapeutics & Vaccines
Category(s): Therapeutics, Therapeutics > Oncology, Therapeutics > Oncology > Oncology (Small Molecules)