UCLA Researchers & Innovators
Industry & Investors
News & Events
About
Concierge
Search Results - therapeutics+%26+vaccines
185
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Copyright: A Comprehensive Platform to Shorten the Period Required for Vaccine Clinical Trial (Case No. 2024-148)
Summary: UCLA researchers have developed a software to accelerate vaccine clinical trial processes by modeling disease behavior and targeting future trial participants. Background: Vaccine clinical trials are time-intensive processes; ones that may be necessary during active pandemics in which time is of short supply. One of the primary factors contributing...
Published: 4/9/2024
|
Inventor(s):
Akihiro Nishi
Keywords(s):
Bioinformatics
,
Clinical Trial
,
Live attenuated vaccine
,
Public Health
,
Simulation & Modeling
,
Software & Algorithms
,
Therapeutics & Vaccines
,
Vaccines
Category(s):
Software & Algorithms > Statistical Models
,
Software & Algorithms > Bioinformatics
Targeted Delivery of IFN-gamma Using Antibody Fusion Proteins (UCLA Case No. 2017-543)
UCLA researchers in the Departments of Microbiology, Immunology & Molecular Genetics (MIMG) and Medicine have developed antibody–cytokine fusion proteins that enable the targeted delivery of active interferon-gamma (IFNγ) for cancer treatment. Interferon-gamma (IFNγ), a type II interferon, is a cytokine released by both natural...
Published: 2/26/2024
|
Inventor(s):
Sherie Morrison
,
John Timmerman
,
Kham (Ryan) Trinh
Keywords(s):
Antibody Delivery Platforms
,
Drug Delivery
,
Immunotherapy
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Platforms > Drug Delivery
,
Platforms > Drug Delivery > Antibody Delivery Platforms
,
Life Science Research Tools
,
Therapeutics > Immunology And Immunotherapy
A novel ER beta ligand prodrug to treat neurodegenerative conditions (UCLA Case No. 2017-168)
Researchers from the Department of Neurology and the Department of Chemistry and Biochemistry at UCLA have developed a novel ERβ ligand prodrug that is structurally designed to confer neuroprotection in neurodegenerative conditions (multiple sclerosis, Alzheimer’s disease, and cognitive deficits of menopause in otherwise healthy women). BACKGROUND: Multiple...
Published: 1/24/2024
|
Inventor(s):
Rhonda Voskuhl
,
Michael Jung
Keywords(s):
Autoimmune
,
Cns
,
Therapeutics & Vaccines
Category(s):
Therapeutics > CNS and Neurology
,
Therapeutics > Autoimmune
,
Therapeutics
Assistive Device to Aid in Identification and Use of Medications (UCLA Case No. 2022-213)
Summary: Researchers in the UCLA Stein Eye Institute have developed a medication assistive device to aid in distinguishing medication bottles and administering medications on the correct schedules for patients, especially those with visual impairment. Background: Many ophthalmic conditions are treated with eye drop medications. These treatments...
Published: 10/17/2023
|
Inventor(s):
Edmund Tsui
,
Jie Deng
,
Holly Huang
,
Jeffrey Li
,
Hyeongtaek Nam
,
Brian Wu
Keywords(s):
3D Printing
,
Hospital Systems And Devices
,
Medical Devices and Materials
,
Monitoring And Recording Systems
,
Ophthalmology
,
Therapeutics & Vaccines
Category(s):
Medical Devices > Monitoring And Recording Systems
,
Therapeutics > Ophthalmology
Alleviating GvHD Using Engineered INKT Cells (UCLA Case No. 2023-019)
SUMMARY: Researchers in UCLA’s Department of Microbiology, Immunology & Molecular Genetics have developed an off-the-shelf cell therapy method for reduction of Graft vs Host Disease (GvHD) following hematopoietic stem cell transplantation. This approach uses engineered third-party iNKT’s to ameliorate severity of GvHD without negatively...
Published: 2/15/2024
|
Inventor(s):
Lili Yang
Keywords(s):
Hematology
,
Stem-Cell Therapy
,
T Cell
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > Hematology
2022-222 A Wearable Aptamer Microneedle Patch for Continuous Minimally-Invasive Biomonitoring
Summary: UCLA researchers in the Department of Bioengineering have developed a novel wearable device for real-time, minimally-invasive medication monitoring. Background: Current medication dosing is determined by taking the average therapeutic dose of a small patient sample size. However, this is often inaccurate for many individuals and the recommended...
Published: 7/19/2023
|
Inventor(s):
Sam Emaminejad
,
Shuyu Lin
,
Jialun Zhu
,
Xuanbing Cheng
Keywords(s):
Biomonitoring
,
Drug
,
Drug Delivery
,
Drug Development
,
Drug Discovery
,
Drug Resistance
,
Invasiveness Of Surgical Procedures
,
Microneedle array
,
non-invasive drug monitoring
,
Personalized Pharmacotherapy
,
Pharmaceutical Drug
,
Pharmacokinetics
,
Pharmacology
,
Prescription Drug
,
Therapeutic Drug Monitoring
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Medical Devices
,
Materials > Nanotechnology
A Novel Device to Produce Autologous Serum Eye Drops at the Point of Care (Case No. 2021-198)
SUMMARY: UCLA researchers in the Stein and Doheny Eye Institutes have designed a device that can produce autologous serum eye drops at the point-of-care, greatly reducing the cost and complexity of the production process. BACKGROUND: Ocular surface diseases afflict hundreds of millions of people per year worldwide. Autologous serum eye drops benefit...
Published: 9/29/2023
|
Inventor(s):
Justin Karlin
Keywords(s):
Human Serum Albumin
,
Medical Devices and Materials
,
Targeted Therapy
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools > Lab Equipment
,
Therapeutics > Ophthalmology
Optimized Lentiviral Vector for Stem Cell Gene Therapy of Hemoglobinopathies
UCLA Case No. 2017-460 Summary UCLA researchers in the Department of Microbiology, Immunology and Molecular Genetics have developed a novel method to produce short lentiviral vectors with tissue-specific expression, with a primary focus on lentiviral vectors for treating sickle cell disease and other disorders of hemoglobin. Background Sickle...
Published: 1/23/2024
|
Inventor(s):
Donald Kohn
,
Roger Hollis
,
Richard Morgan
Keywords(s):
Drug Delivery
,
Gene Editing Systems
,
Gene Therapy
,
Genetic Disease
,
Life Science Research Tools
,
Plasmids / Vectors
,
Research Methods
,
Therapeutics & Vaccines
,
Viral Delivery Systems
Category(s):
Life Science Research Tools > Plasmids/Vectors
,
Life Science Research Tools
,
Life Science Research Tools > Research Methods
,
Platforms > Drug Delivery
,
Therapeutics
,
Platforms > Drug Delivery > Viral Delivery Systems
,
Therapeutics > Gene Therapy And Editing
2018-438 A DNA CONSTRUCT FOR TARGETING THERAPEUTIC MOLECULES TO DISEASED TISSUE BY IMMUNE CELLS
INTRODUCTION:UCLA researchers in the Departments of Integrative Biology & Physiology and Pathology & Laboratory Medicine have developed a novel construct for targeting therapeutic biological molecules specifically to diseased tissue, using immune cells as a delivery system. BACKGROUND:Drug delivery is the process of administering a pharmaceutical...
Published: 7/19/2023
|
Inventor(s):
Keywords(s):
Drug Delivery
,
Nucleic Acid Platform Systems
,
Nucleic Acids
,
Therapeutics & Vaccines
Category(s):
Platforms > Drug Delivery > Nucleic Acid Platform Systems
,
Platforms > Drug Delivery > Nucleic Acids
2018-680: Single-Chain Bispecific Chimeric Antigen Receptor Targeting BCMA And CS1 For The Treatment Of Multiple Myeloma
SUMMARY UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a single-chain bispecific chimeric antigen receptor targeting BCMA and CS1 for treating multiple myeloma. BACKGROUND Multiple myeloma (MM) is a cancer of the plasma cells that accounts for over 30,000 new diagnoses each year, according to the American...
Published: 1/16/2024
|
Inventor(s):
Yvonne Chen
,
Eugenia Zah
Keywords(s):
Hematology
,
Immunotherapy
,
Life Science Research Tools
,
Therapeutics & Vaccines
Category(s):
Life Science Research Tools
,
Therapeutics
,
Therapeutics > Hematology
,
Therapeutics > Immunology And Immunotherapy
1
2
3
4
5
6
7
8
9
10
...